PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Araha.13526s0009.1.p
Organism
Arabidopsis halleri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 194aa    MW: 21639.3 Da    PI: 4.9167
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Araha.13526s0009.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH12.90.000240653155
                          ....TTS-STCHHHHHHHHHHHHHHH CS
                   HLH 31 s.kapskKlsKaeiLekAveYIksLq 55
                          + + ++kKls ++++ +A +YI +Lq
  Araha.13526s0009.1.p 40 TvAHHNKKLSVSATVSHALKYIPELQ 65
                          147799*****************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474593.49E-53783IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0010106Biological Processcellular response to iron ion starvation
GO:0055072Biological Processiron ion homeostasis
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 194 aa     Download sequence    Send to blast
MCALVPPLYS NFGWPCGDNS FYEDEDVTNT FIDFPLPDLT VAHHNKKLSV SATVSHALKY  60
IPELQEQVKK LIKKKEELTF QISGRRDLVY TDQNSKPERT VTSYASTVSA TRLGETEVMV  120
QISSLQADKC SFGNVLSGVE EDGLVLVDAS SSRSQGERLF YSLHLQMENG KVNSEELGDR  180
LLYLYEKCGH SFT*
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in metal homeostasis. Confers tolerance to high zinc (Zn) and nickel (Ni). {ECO:0000269|PubMed:18088336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAraha.13526s0009.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up regulated by iron deficiency in roots and leaves, as well as by nickel, high zinc or high copper treatments. Repressed by heat treatment, high iron, low copper and low zinc treatments. {ECO:0000269|PubMed:12679534, ECO:0000269|PubMed:17516080, ECO:0000269|PubMed:18088336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0056620.0AC005662.3 Arabidopsis thaliana chromosome 2 clone F13H10 map CIC11C08, complete sequence.
GenBankAY0746350.0AY074635.1 Arabidopsis thaliana At2g41240/F13H10.21 mRNA, complete cds.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002881763.11e-123transcription factor bHLH100
SwissprotQ9ZVB51e-107BH100_ARATH; Transcription factor bHLH100
TrEMBLD7LGK61e-122D7LGK6_ARALL; Predicted protein
STRINGAl_scaffold_0004_27341e-122(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM48228153
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G41240.11e-101basic helix-loop-helix protein 100
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Maurer F,Naranjo Arcos MA,Bauer P
    Responses of a triple mutant defective in three iron deficiency-induced Basic Helix-Loop-Helix genes of the subgroup Ib(2) to iron deficiency and salicylic acid.
    PLoS ONE, 2014. 9(6): p. e99234
    [PMID:24919188]
  3. Martínez-Trujillo M, et al.
    Chromate alters root system architecture and activates expression of genes involved in iron homeostasis and signaling in Arabidopsis thaliana.
    Plant Mol. Biol., 2014. 86(1-2): p. 35-50
    [PMID:24928490]
  4. Van Dingenen J, et al.
    Strobilurins as growth-promoting compounds: how Stroby regulates Arabidopsis leaf growth.
    Plant Cell Environ., 2017. 40(9): p. 1748-1760
    [PMID:28444690]
  5. Wang C,Yao X,Yu D,Liang G
    Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana.
    Planta, 2017. 246(3): p. 421-431
    [PMID:28451750]
  6. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  7. Kailasam S,Wang Y,Lo JC,Chang HF,Yeh KC
    S-Nitrosoglutathione works downstream of nitric oxide to mediate iron-deficiency signaling in Arabidopsis.
    Plant J., 2018. 94(1): p. 157-168
    [PMID:29396986]
  8. Kurt F,Filiz E
    Genome-wide and comparative analysis of bHLH38, bHLH39, bHLH100 and bHLH101 genes in Arabidopsis, tomato, rice, soybean and maize: insights into iron (Fe) homeostasis.
    Biometals, 2018. 31(4): p. 489-504
    [PMID:29546482]