PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Araha.1486s0003.1.p

Organism

Arabidopsis halleri

Taxonomic ID

81970

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

BES1

Protein Properties

Length: 248aa MW: 26783.8 Da PI: 9.9053

Description

BES1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Araha.1486s0003.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	DUF822	208.6	1.7e-64	17	156	2	144
DUF822 2 gsgrkptwkErEnnkrRERrRRaiaakiyaGLRaqGnyklpkraDnneVlkALcreAGwvvedDGttyrkgskpleeaeaagssasaspe 91 +++rkp+w+ErEnn+rRERrRRa+aakiy+GLRaqGny+lpk++DnneVlkALc eAGwvve+DGttyrkg kpl ++agss++a+p Araha.1486s0003.1.p 17 ATRRKPSWRERENNRRRERRRRAVAAKIYTGLRAQGNYNLPKHCDNNEVLKALCSEAGWVVEEDGTTYRKGHKPL-PGDMAGSSSRATPY 105 689**********************************************************************.********** PP DUF822 92 sslqsslkssalaspvesysaspksssfpspssldsislasaasllpvlsvls 144 ss ++s+ ss++ sp+ sy+ sp+sssfpsps++ ++ ++++p+l++ + Araha.1486s0003.1.p 106 SSHNQSPLSSTFDSPILSYQVSPSSSSFPSPSRVGDPHNI--STIFPFLRNGG 156 *******************************8776655..67888888775 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF05687	2.7E-61	18	139	IPR008540	BES1/BZR1 plant transcription factor, N-terminal

Sequence ? help Back to Top
Protein Sequence Length: 248 aa Download sequence Send to blast
MTSDGATSTS AAAAAMATRR KPSWRERENN RRRERRRRAV AAKIYTGLRA QGNYNLPKHC 60 DNNEVLKALC SEAGWVVEED GTTYRKGHKP LPGDMAGSSS RATPYSSHNQ SPLSSTFDSP 120 ILSYQVSPSS SSFPSPSRVG DPHNISTIFP FLRNGGIPSS LPPLRISNSA PVTPPPFSAS 180 MVPTSPTFNL VKPAPQQLSP NTAATQEIGQ SSEFKFENSQ VKPWEGERIH DVAMEDLELT 240 LGNGKSS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zd4_A	4e-37	19	101	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_B	4e-37	19	101	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_C	4e-37	19	101	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_D	4e-37	19	101	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	18	37	RRKPSWRERENNRRRERRRR

Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610). {ECO:0000269\|PubMed:12007405, ECO:0000269\|PubMed:15680330, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19170933, ECO:0000269\|PubMed:20139304, ECO:0000269\|PubMed:24838002, ECO:0000269\|PubMed:24981610}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Araha.1486s0003.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF134217	0.0	AF134217.1 Arabidopsis thaliana 107 protein (107) mRNA, complete cds.
GenBank	AY065041	0.0	AY065041.1 Arabidopsis thaliana At1g19350/F18O14_4 mRNA, complete cds.
GenBank	AY086340	0.0	AY086340.1 Arabidopsis thaliana clone 24157 mRNA, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_973863.1	2e-90	Brassinosteroid signaling positive regulator (BZR1) family protein
Refseq	XP_009117543.1	1e-90	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_009117544.1	1e-90	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_009117545.1	1e-90	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_013664647.1	1e-90	protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_020870402.1	2e-90	protein BRASSINAZOLE-RESISTANT 2
Refseq	XP_020870404.1	2e-90	protein BRASSINAZOLE-RESISTANT 2
Swissprot	Q9LN63	2e-91	BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
TrEMBL	A0A078G5C8	9e-89	A0A078G5C8_BRANA; BnaA09g44210D protein
TrEMBL	A0A178W3G4	4e-89	A0A178W3G4_ARATH; BZR2
TrEMBL	A0A397YB44	2e-89	A0A397YB44_BRACM; Uncharacterized protein
TrEMBL	A0A3P5Y899	9e-89	A0A3P5Y899_BRACM; Uncharacterized protein
TrEMBL	D7KHC7	4e-89	D7KHC7_ARALL; Bri1-ems-suppressor 1
TrEMBL	F4HP45	5e-89	F4HP45_ARATH; Brassinosteroid signaling positive regulator (BZR1) family protein
TrEMBL	M4EQK6	9e-89	M4EQK6_BRARP; Uncharacterized protein
STRING	AT1G19350.3	9e-90	(Arabidopsis thaliana)
STRING	Bra031077.1-P	1e-89	(Brassica rapa)
STRING	fgenesh2_kg.1__2112__AT1G19350.4	6e-90	(Arabidopsis lyrata)
STRING	Bostr.7128s0539.1.p	6e-90	(Boechera stricta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM15511	11	17

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19350.3	3e-84	BES1 family protein

Link Out ? help Back to Top
Phytozome	Araha.1486s0003.1.p

Publications ? help Back to Top
Salazar-Henao JE,Lehner R,Betegón-Putze I,Vilarrasa-Blasi J,Caño-Delgado AI BES1 regulates the localization of the brassinosteroid receptor BRL3 within the provascular tissue of the Arabidopsis primary root. J. Exp. Bot., 2016. 67(17): p. 4951-61 [PMID:27511026] Nolan T, et al. Identification of Brassinosteroid Target Genes by Chromatin Immunoprecipitation Followed by High-Throughput Sequencing (ChIP-seq) and RNA-Sequencing. Methods Mol. Biol., 2017. 1564: p. 63-79 [PMID:28124247] Ye H, et al. RD26 mediates crosstalk between drought and brassinosteroid signalling pathways. Nat Commun, 2017. 8: p. 14573 [PMID:28233777] Nolan TM, et al. Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. Dev. Cell, 2017. 41(1): p. 33-46.e7 [PMID:28399398] Yang M, et al. SINAT E3 Ligases Control the Light-Mediated Stability of the Brassinosteroid-Activated Transcription Factor BES1 in Arabidopsis. Dev. Cell, 2017. 41(1): p. 47-58.e4 [PMID:28399399] Chen J, et al. Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses. Plant Cell, 2017. 29(6): p. 1425-1439 [PMID:28576847] Yang M,Wang X Multiple Ways of BES1/BZR1 Degradation to Decode Distinct Developmental and Environmental Cues in Plants. Mol Plant, 2017. 10(7): p. 915-917 [PMID:28629641] Saito M,Kondo Y,Fukuda H BES1 and BZR1 Redundantly Promote Phloem and Xylem Differentiation. Plant Cell Physiol., 2018. 59(3): p. 590-600 [PMID:29385529] Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]