PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Araip.FR26E
Organism
Arachis ipaensis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family E2F/DP
Protein Properties Length: 516aa    MW: 57336.7 Da    PI: 5.185
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Araip.FR26EgenomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.71.7e-27225290171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                  r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Araip.FR26E 225 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 290
                  6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.9E-29223292IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.0E-35225290IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.62E-17225288IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.2E-24227290IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146603.34E-45301407No hitNo description
SuperFamilySSF1440741.39E-30303407No hitNo description
PfamPF164215.3E-32306405IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 516 aa     Download sequence    Send to blast
MSGTRAPPAA ASPSEQIMRR QLPLSAMKPP FAASVDYHRF APDHLHHNRR TVDHEPEAIV  60
VNSSVWITCL VVNLVELVAD ELEELNYGVH NVKCRLPSPS PHGSDILVLR EGSKGLAKQF  120
RLNDFDYPNI GLGGFIIYTF LGKTTNGDIC LHVLRLHFSG DFEVDSGDRV NHVSMGAANN  180
PFQTPKSGKI GKGGKSSRLT KCNRSGPQTP GSPSGNNLTP VGPCRYDSSL GLLTKKFINL  240
IKQAEDGILD LNKAADTLEV QKRRIYDITN VLEGIGLIEK KLKNRIQWKG LDVSRPGEPE  300
DSFSSLQAEV ENLTMKECRL DEQIREMQER LSDLSENENS EKLLFVTEED IKNLPCFQNE  360
TLMAIKAPHG TTLEVSDPDE AVDYPQRRYR IVLRSTMGPI DVYLVSQFEG KFEEINGADV  420
APKFQPTPEF KNHQPTVVVE DNGKDIAVQG QDGQIPSSDF TSTQDFVSGI VKIVPSDVDK  480
PRSSIKTFFS PSLQSDADYW LLSDADVSIT DMWRTE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-26220291274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAraip.FR26E
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016187597.10.0transcription factor E2FB isoform X3
RefseqXP_025641548.10.0transcription factor E2FB isoform X2
SwissprotQ9FV711e-126E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A445E5510.0A0A445E551_ARAHY; Uncharacterized protein
STRINGXP_004506213.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF2872522
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.31e-123E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]