PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Araip.HB9YP
Organism
Arachis ipaensis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family E2F/DP
Protein Properties Length: 378aa    MW: 42311.5 Da    PI: 9.7673
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Araip.HB9YPgenomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP70.71.7e-221681171
      E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                 rk+k L+ll+++fl+l+++ + + + l+++a +L    v  +rRRiYDi+N+Le+++++++k+kn+++wkg
  Araip.HB9YP 16 RKQKALGLLCTNFLSLYNRHDVQFIGLDDAAARL---GV--ERRRIYDIVNILESIGVLARKAKNQYTWKG 81
                 79*****************999************...**..****************************98 PP
2E2F_TDP56.83.7e-181692391171
      E2F_TDP  11 qkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                  +kf++ + +s  ++++l+e+a+ L+ +      +++k+RR+YDi+NVL+++nliek     ++k+++rw g
  Araip.HB9YP 169 SKFISRCLSSMIEMISLDEAANLLLGDghsssLMRTKVRRLYDIANVLSSMNLIEKthttdTRKPAFRWLG 239
                  589******999*******************9999*************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.8E-241482IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.93E-151579IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.7E-261681IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.2E-191781IPR003316E2F/DP family, winged-helix DNA-binding domain
SMARTSM013721.2E-19166239IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.4E-16169240IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.5E-14170239IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467857.07E-10173240IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 378 aa     Download sequence    Send to blast
MASSASSSRH PVPQSRKQKA LGLLCTNFLS LYNRHDVQFI GLDDAAARLG VERRRIYDIV  60
NILESIGVLA RKAKNQYTWK GFGAIPGAFH ELKEEGLREN TYAFEGGNDN LKGSDDEDDE  120
EAFSNTGTGS QNDKSNSNSN SNSTTLSKSL KNGNFSFFPF SCFFQRKLSK FISRCLSSMI  180
EMISLDEAAN LLLGDGHSSS LMRTKVRRLY DIANVLSSMN LIEKTHTTDT RKPAFRWLGL  240
RGKAPNESIQ NCSNPNESRK RAFGTDVTNI SFERNIVELG DFASKKLKKL DNGSGIGQAN  300
SFQQASKGFQ FGPFAPSYVP KVGTPENNSV KKVHDWDSLA IKHRPQYQNQ ALRELFSHYM  360
EAWKSWYSEV VGKNPMQI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-34152313228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAraip.HB9YP
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020966538.10.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-111E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A445B0F20.0A0A445B0F2_ARAHY; Uncharacterized protein
STRINGGLYMA05G01760.21e-164(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-110DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]