PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bostr.1460s0076.1.p
Organism
Boechera stricta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera
Family E2F/DP
Protein Properties Length: 353aa    MW: 39783.6 Da    PI: 8.6448
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bostr.1460s0076.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP69.93e-222085171
              E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                         rkeksL++l ++fl+l+++ +++ + l+++a +L    v  +rRRiYD++N+Le++++++++ kn ++wkg
  Bostr.1460s0076.1.p 20 RKEKSLGVLVSNFLRLYNRDDADLIGLDDAAGKL---GV--ERRRIYDVVNILESIGIVARRGKNMYSWKG 85
                         79********************************...**..****************************98 PP
2E2F_TDP86.12.7e-27144224171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                          rkeksL+ll+q+f+k++ +s+++ +tl+++ak+L+s+     ++k+k+RR+YDi+NV++++nliek     ++k+++rw g
  Bostr.1460s0076.1.p 144 RKEKSLWLLSQNFVKMFLCSDDDLITLDSAAKALLSDsqdpvHMKTKVRRLYDIANVFSSMNLIEKthipeTRKPAYRWLG 224
                          79*****************************************************************************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.1E-231786IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.31E-151983IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-252085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.3E-182185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.105.6E-23141226IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-33144224IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.2E-20145224IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.31E-13146225IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 353 aa     Download sequence    Send to blast
MSSSIVSHDV ESLGLQSYSR KEKSLGVLVS NFLRLYNRDD ADLIGLDDAA GKLGVERRRI  60
YDVVNILESI GIVARRGKNM YSWKGFGEVP RSLNELKEEG MRERFSISST NNSDKVSNDG  120
EREESFSLTP DDQENSSSSK IDQRKEKSLW LLSQNFVKMF LCSDDDLITL DSAAKALLSD  180
SQDPVHMKTK VRRLYDIANV FSSMNLIEKT HIPETRKPAY RWLGSESIAE KGSSLCNSDK  240
PKKRVFGREV TNLRATRNKT DCSSNCKQIG YKKHDEENTE QESKPAAGNY VFGPFSPTGA  300
SKKNNVGKGR LQEIETLASS TYKPQYCNQE ITGLLGHFTE AWKKWYAELD RK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-37192163228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBostr.1460s0076.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0745320.0AB074532.1 Arabidopsis thaliana mRNA for E2F-like repressor E2L2, complete cds.
GenBankAY0930240.0AY093024.1 Arabidopsis thaliana unknown protein (At3g01330) mRNA, complete cds.
GenBankBT0004120.0BT000412.1 Arabidopsis thaliana unknown protein (At3g01330) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006297996.10.0E2F transcription factor-like E2FF
SwissprotQ8RWL00.0E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLR0HMF00.0R0HMF0_9BRAS; Uncharacterized protein
STRINGBostr.1460s0076.1.p0.0(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.10.0DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]