PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bostr.26527s0055.1.p
Organism
Boechera stricta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera
Family E2F/DP
Protein Properties Length: 460aa    MW: 50515.9 Da    PI: 4.3995
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bostr.26527s0055.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.61.9e-27127192171
               E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                           r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+i+wkg
  Bostr.26527s0055.1.p 127 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIQWKG 192
                           6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.7E-29124194IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.45E-17127190IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.9E-35127192IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.5E-24129192IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.27E-46203309No hitNo description
SuperFamilySSF1440744.45E-32205309No hitNo description
PfamPF164211.7E-32208307IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 460 aa     Download sequence    Send to blast
MSEEPQQFPP SKRQHHPSLS SMKPPLVAPG EYHRFDAAET RLGGAADQVV SEAIVIKSTL  60
KRKTDAVNQI AEPNELNTGV LQTPISGKGG KAKKTSRSVK SNKSGTQASG SNAGSPGNNF  120
AQAGTCRYDS SLGLLTKKFI NLIKQAEDGI LDLNKAADTL EVQKRRIYDI TNVLEGIGLI  180
EKTLKNRIQW KGLDVSKPGE TIESIANLQD EVQNLTAEEA KLDDQIRESQ ERLTSLSEDE  240
NNKRLLFVTE DDIKNLPCFQ NKTLIAVKAP HGTTLEVPDP DEAGGYPQRR YRIILRSTMG  300
PIDVYLVSQF EESFEDIPHA DGPSNVPDEP SNLPSTSGLP ENHDVAMTME EDSTERNMET  360
QELDDTQRVY SDIESHDFVD GIMKIVPPDL DMGVDYWLRS EVGEVSLTDL WPDESGPDWN  420
QMVSFDQDHA GPSNTTLEQP QTPSSPTPED STATRSTGS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-24127193774PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBostr.26527s0055.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2425800.0AF242580.1 Arabidopsis thaliana E2F transcription factor-1 E2F1 mRNA, complete cds.
GenBankAJ2945330.0AJ294533.1 Arabidopsis thaliana mRNA for E2F-related protein (e2Fb gene).
GenBankAY1364790.0AY136479.1 Arabidopsis thaliana expressed protein (At5g22220) mRNA, complete cds.
GenBankBT0066100.0BT006610.1 Arabidopsis thaliana At5g22220 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020876640.10.0transcription factor E2FB
SwissprotQ9FV710.0E2FB_ARATH; Transcription factor E2FB
TrEMBLD7M0V20.0D7M0V2_ARALL; Uncharacterized protein
STRINGBostr.26527s0055.1.p0.0(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.20.0E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]