PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bostr.2902s0230.1.p
Organism
Boechera stricta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera
Family E2F/DP
Protein Properties Length: 354aa    MW: 40021.3 Da    PI: 8.7179
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bostr.2902s0230.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP71.69.1e-231176171
              E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                         rkeksL++l ++flkl+++ + + + l+++a +L    v  +rRRiYD++N+Le+++l++++ kn+++wkg
  Bostr.2902s0230.1.p 11 RKEKSLGVLVSNFLKLYNRDDVDLIGLDDAAGKL---GV--ERRRIYDVVNILESIGLVARRGKNQYSWKG 76
                         79*****************999************...**..****************************98 PP
2E2F_TDP80.41.6e-25136216171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                          +keksL++l+q+f+kl+ +s+++ +tl+ ++k+L+++     ++++k+RR+YDi+NV++++nliek     ++k+++rw g
  Bostr.2902s0230.1.p 136 KKEKSLWQLAQNFVKLFLCSDDDLITLDGATKALLNDsqdptNMRTKVRRLYDIANVFSSMNLIEKthipeTKKPAYRWLG 216
                          69********************************************************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.1E-23877IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467857.17E-161074IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.8E-261176IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.1E-191276IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.104.0E-21134218IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.7E-31136216IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.4E-19137216IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.93E-12138217IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 354 aa     Download sequence    Send to blast
MDSLNPQPYS RKEKSLGVLV SNFLKLYNRD DVDLIGLDDA AGKLGVERRR IYDVVNILES  60
IGLVARRGKN QYSWKGFGQV PRALSELKEE GMKEKFGIIP CVTNSEMVLY EEEREESFKL  120
TPDDQENSPS PKLDNKKEKS LWQLAQNFVK LFLCSDDDLI TLDGATKALL NDSQDPTNMR  180
TKVRRLYDIA NVFSSMNLIE KTHIPETKKP AYRWLGSKAI SENRFLAGSA SLCDHNEPKK  240
RAFGTEITNF NAKRNKTDCS KDRKHYGNQN TNSVIKKEPC DLKPDVKNFA FGSSTPAGTS  300
EMNNIGNNIR PRLGVLEALS SIYQPQYCNP ELFGLLAHYK EAFKSSQEEF GRK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-3472081228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00511DAPTransfer from AT5G14960Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapBostr.2902s0230.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0745310.0AB074531.1 Arabidopsis thaliana mRNA for E2F-like repressor E2L1, complete cds.
GenBankAB4937500.0AB493750.1 Arabidopsis thaliana At5g14960 mRNA for hypothetical protein, partial cds, clone: RAAt5g14960.
GenBankAJ4178350.0AJ417835.1 Arabidopsis thaliana mRNA for transcription factor E2Fd (e2Fd gene).
GenBankBT0155400.0BT015540.1 Arabidopsis thaliana At5g14906 mRNA sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006288061.10.0E2F transcription factor-like E2FD
SwissprotQ9LFQ90.0E2FD_ARATH; E2F transcription factor-like E2FD
TrEMBLR0GVN70.0R0GVN7_9BRAS; Uncharacterized protein
STRINGBostr.2902s0230.1.p0.0(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G14960.10.0DP-E2F-like 2