PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bradi1g63780.1.p
Common NameBRADI_1g63780, LOC100839437
Organism
Brachypodium distachyon
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family EIL
Protein Properties Length: 651aa    MW: 71907.6 Da    PI: 4.7823
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bradi1g63780.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3505.42.8e-154794701354
                       XXXXXXXXXXXXXXXXXXXXXXX..XXXXX......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
              EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaa.....tgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegas 88 
                       eel++rmw+d+m+lkrlke ++++ +++         g  k ++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gas
  Bradi1g63780.1.p  79 EELERRMWRDRMKLKRLKELQQSRGKEQAGGggmgaDGGLKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPVSGAS 171
                       8*********************988555554776655566889************************************************** PP

                       XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHH CS
              EIN3  89 dsLraWWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelww 181
                       d+LraWWkekv+fdrngpaai+kyqa+n+++++es+l + +++++hsl+elqDTtlgSLLsalmqhc+ppqrrfplekgv+pPWWP+G+e+ww
  Bradi1g63780.1.p 172 DNLRAWWKEKVRFDRNGPAAIAKYQADNAVPGSESDLGS-GTASPHSLQELQDTTLGSLLSALMQHCEPPQRRFPLEKGVSPPWWPSGDEEWW 263
                       *************************************88.***************************************************** PP

                       HHHT--TT--.-----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXXXX.....XXXX CS
              EIN3 182 gelglskdqgtppykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsahss.....slrk 269
                       +elg++kdqg+ppykkphdlkkawkvsvLtavikhmsp+ie+ir+l+rqsk+lqdkm+ake  ++l+v++qee+++ ++++  +         
  Bradi1g63780.1.p 264 PELGIPKDQGPPPYKKPHDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELYMRLHPGARppmpsGGIA 356
                       *********************************************************************************944344432223 PP

                       XXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX...............................XXXXXXXXXXXXXXXXXXXXX......XX CS
              EIN3 270 qspkvtlsceqkedvegkkeskikhvqavktta...............................gfpvvrkrkkkpsesakvsskevsrtcqs 331
                       ++ ++++s++ ++dv++ ++ k  ++ ++k ++                               +++ v+kr + ++e++ + +++v +tc++
  Bradi1g63780.1.p 357 SAISFNASSS-EYDVDVADDCKGDEAGTHKMAMadptafnlgaamlndkflmpelpmnmkeeaaDVEYVQKRGSATTEPELMLNNRV-YTCNN 447
                       5555555555.99***7777777777776666578888*********************************************9986.***** PP

                       XXXXX.XXXXXXXXXXXXXXXXX CS
              EIN3 332 sqfrgsetelifadknsisqney 354
                        q+++s++  +f d+n++++++y
  Bradi1g63780.1.p 448 GQCPQSDYGYGFLDRNARNSHQY 470
                       *********************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048732.3E-13179336No hitNo description
Gene3DG3DSA:1.10.3180.103.8E-74211344IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167681.06E-60215340IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 651 aa     Download sequence    Send to blast
MMGGGLVMDQ GMVFSGVHNF VDLLQQNGGD KNLGFGSLMP QTSSGDQCVM GEGDLVDPPA  60
DNFPDAGDDD SDDDVDDIEE LERRMWRDRM KLKRLKELQQ SRGKEQAGGG GMGADGGLKP  120
RQSQEQARRK KMSRAQDGIL KYMLKMMEVC RAQGFVYGII PEKGKPVSGA SDNLRAWWKE  180
KVRFDRNGPA AIAKYQADNA VPGSESDLGS GTASPHSLQE LQDTTLGSLL SALMQHCEPP  240
QRRFPLEKGV SPPWWPSGDE EWWPELGIPK DQGPPPYKKP HDLKKAWKVS VLTAVIKHMS  300
PDIEKIRRLV RQSKCLQDKM TAKEISTWLA VVKQEEELYM RLHPGARPPM PSGGIASAIS  360
FNASSSEYDV DVADDCKGDE AGTHKMAMAD PTAFNLGAAM LNDKFLMPEL PMNMKEEAAD  420
VEYVQKRGSA TTEPELMLNN RVYTCNNGQC PQSDYGYGFL DRNARNSHQY ACKYNDPLPP  480
TVAVENKPPP PPPAQQVFPT AYNQPNQALN NLDLDFSLPM DGHRSITELM NMYDNNMANK  540
STSSNDDVTI IERPNALAPR MQMDEGFFGQ GNGIGGNGGG LFDDVGNMMQ QQQQPQAQAP  600
QQFFIRDDTQ FGNQMGNITG SSDFRFGSGF NMSGTVDYPQ QKNDGPNWYY *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A3e-732133441132Protein ETHYLENE INSENSITIVE 3
4zds_B3e-732133441132Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapBradi1g63780.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2483110.0AK248311.1 Hordeum vulgare subsp. vulgare cDNA clone: FLbaf51m23, mRNA sequence.
GenBankAK3638910.0AK363891.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2019M20.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003558012.10.0ETHYLENE INSENSITIVE 3-like 1 protein
RefseqXP_010228682.10.0ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M410.0EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLI1H5Z20.0I1H5Z2_BRADI; Uncharacterized protein
STRINGBRADI1G63780.10.0(Brachypodium distachyon)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP63838168
Representative plantOGRP5631682
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.11e-165ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]