PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bradi4g42050.3.p
Common NameBRADI_4g42050, LOC100839650
Organism
Brachypodium distachyon
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family E2F/DP
Protein Properties Length: 413aa    MW: 45483.2 Da    PI: 4.4068
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bradi4g42050.3.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.22.2e-2697162171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       r+++sL+llt+kfl+ll+ ++ g+v+ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  Bradi4g42050.3.p  97 RYDSSLGLLTKKFLNLLKGAPGGMVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 162
                       6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.4E-2895163IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.0E-3497162IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.63E-1697160IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.7E-2399162IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146604.62E-49173279No hitNo description
SuperFamilySSF1440741.86E-32174279No hitNo description
PfamPF164211.7E-33178277IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 413 aa     Download sequence    Send to blast
MGMGVFWCWW RQNCRILLAV LKRKHNREDN GVAESNDWMM SPGYANAASS PVPTPPSGKG  60
SKHSTKLKSA KGQKSCSQAP LFSGSPGNPA TPVGGCRYDS SLGLLTKKFL NLLKGAPGGM  120
VDLNNAAETL EVQKRRIYDI TNVLEGIGLI EKKLKNNIRW KGIDDSRPGE VSDDMSILQG  180
DIEALTLQEH SVDEQISEMR DKLRELTEDE NNQKWLYVTE DDIKSLSCFQ NQTLIAIKAP  240
HGTTLEVPDP DEVNDYPQRR YRIVLRSTMG PIDVYLVSQF EEMSGMETPP RPAQTISTNS  300
LENPRTPLAA GSNKDAEMQL NIQDEPIIPP DAPTSSQDIG GMMKIVPSDL DADADYWLLS  360
DTGVSITDMW KTAPEVEWDG MDINADDFLE VSTPQQQGQL PSDIADLPSC IS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-2289163274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapBradi4g42050.3.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010238694.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY01e-116E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2K2CTQ40.0A0A2K2CTQ4_BRADI; Uncharacterized protein
STRINGBRADI4G42050.10.0(Brachypodium distachyon)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-109E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]