PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bradi5g09640.6.p
Common NameBRADI_5g09640, LOC100830591
Organism
Brachypodium distachyon
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family E2F/DP
Protein Properties Length: 423aa    MW: 46100.1 Da    PI: 5.8759
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bradi5g09640.6.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP85.24.9e-27146211171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       r+++sL+llt+kf++ll+++e+gi++ln++a++L   dv  ++RRiYDi+NVLe+++liekk kn i+wkg
  Bradi5g09640.6.p 146 RYDNSLGLLTKKFINLLRQAEDGIIDLNDAAETL---DV--RKRRIYDITNVLEGIGLIEKKIKNTIHWKG 211
                       689*******************************...**..9***************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.0E-28143212IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-34146211IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.32E-17146209IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023195.0E-24148211IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.26E-41221328No hitNo description
SuperFamilySSF1440743.4E-29224328No hitNo description
PfamPF164211.6E-28226326IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 423 aa     Download sequence    Send to blast
MSGGGRPQVA RKVVQSVQRR VPLAPRLPPI AVPSEYHRFP VPLPSAAAAA ASRGSVRGDI  60
EEGIVTTKPL KRKAPCQKSD AAELTRRVMT SPGFTEGLGS PLTTPVSGKA SRTYKSKAKC  120
SKSGPQTPIS NAGSPGNPLT PAGSCRYDNS LGLLTKKFIN LLRQAEDGII DLNDAAETLD  180
VRKRRIYDIT NVLEGIGLIE KKIKNTIHWK GLDGSGSNSD NVVSVLQTEV ENLNLQEEVL  240
DEHISEMREK IREFIEEESN QRWLYLTEDD IKGLPCFQNG TLIAIKAPDG TTLEVPDPDE  300
QAGDYIKRRY RIVIRSTRGS IDLYLVSKFD EKIEELVDVA TPPRQAGLAT PTSMKGFRAI  360
EAGQSSGAKD MSPNIQYIHK TPDLNAQDFG GATITPEVDT DADYWILTDG DDVSITDMWK  420
TA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A8e-25141212274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBradi5g09640.6.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003581217.10.0transcription factor E2FA isoform X1
RefseqXP_010239888.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY01e-111E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2K2CG900.0A0A2K2CG90_BRADI; Uncharacterized protein
STRINGTraes_2DL_BD8048C15.10.0(Triticum aestivum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-101E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]