PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Brast02G164500.1.p
Organism
Brachypodium stacei
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family EIL
Protein Properties Length: 650aa    MW: 71983.7 Da    PI: 4.8747
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Brast02G164500.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3506.31.5e-154794701354
                         XXXXXXXXXXXXXXXXXXXXXXX..XXXXX........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
                EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaa.......tgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpv 84 
                         eel++rmw+d+m+lkrlke ++++   ke+a        g  k ++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv
  Brast02G164500.1.p  79 EELERRMWRDRMKLKRLKELQQSRG--KEHAggdggmgDGGLKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPV 167
                         8*******************99987..444445888776667899********************************************** PP

                         XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH--- CS
                EIN3  85 egasdsLraWWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPt 175
                         +gasd+LraWWkekv+fdrngpaai+kyqa+n+++++es+l + +++++hsl+elqDTtlgSLLsalmqhc+ppqrrfplekgv+pPWWP+
  Brast02G164500.1.p 168 SGASDNLRAWWKEKVRFDRNGPAAIAKYQADNAVPGSESDLAS-GTASPHSLQELQDTTLGSLLSALMQHCEPPQRRFPLEKGVSPPWWPS 257
                         *****************************************66.*********************************************** PP

                         S--HHHHHHT--TT--.-----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXXXX. CS
                EIN3 176 GkelwwgelglskdqgtppykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsahss. 265
                         G+e+ww+elg++kdqg+ppykkphdlkkawkvsvLtavikhmsp+ie+ir+l+rqsk+lqdkm+ake  ++l+v++qee+++ ++++  + 
  Brast02G164500.1.p 258 GDEEWWPELGIPKDQGPPPYKKPHDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELYMRLHPGARp 348
                         ***************************************************************************************9443 PP

                         ....XXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX...............................XXXXXXXXXXXXXXXXXXX CS
                EIN3 266 ....slrkqspkvtlsceqkedvegkkeskikhvqavktta...............................gfpvvrkrkkkpsesakvs 321
                                 ++ ++++s++ ++dv++ ++ k  ++ ++k ++                               +++ v+kr ++++e++ + 
  Brast02G164500.1.p 349 pmpsGGIASAISFNASSS-EYDVDVADDCKGDEAGTHKMAMadptafnlgaailndkflmpelpmnmkeeaaDVEYVQKRSSPTTEPELML 438
                         444322235555555555.99***7777777777776666578888********************************************* PP

                         XX......XXXXXXX.XXXXXXXXXXXXXXXXX CS
                EIN3 322 skevsrtcqssqfrgsetelifadknsisqney 354
                         +++v +tc++ q+++s++  +f d+n++++++y
  Brast02G164500.1.p 439 NNRV-YTCNNGQCPQSDYGYGFLDRNARNSHQY 470
                         9976.**************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048734.7E-13179336No hitNo description
Gene3DG3DSA:1.10.3180.103.8E-74210344IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167681.06E-60215340IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 650 aa     Download sequence    Send to blast
MMGGGLVMDQ GMVFSGVHNF VDLLQQNGGD KNLGFGSLMP QTSSGDQCVM GEGDLVDPPS  60
DNFPDAGEDD SDDDVDDIEE LERRMWRDRM KLKRLKELQQ SRGKEHAGGD GGMGDGGLKP  120
RQSQEQARRK KMSRAQDGIL KYMLKMMEVC RAQGFVYGII PEKGKPVSGA SDNLRAWWKE  180
KVRFDRNGPA AIAKYQADNA VPGSESDLAS GTASPHSLQE LQDTTLGSLL SALMQHCEPP  240
QRRFPLEKGV SPPWWPSGDE EWWPELGIPK DQGPPPYKKP HDLKKAWKVS VLTAVIKHMS  300
PDIEKIRRLV RQSKCLQDKM TAKEISTWLA VVKQEEELYM RLHPGARPPM PSGGIASAIS  360
FNASSSEYDV DVADDCKGDE AGTHKMAMAD PTAFNLGAAI LNDKFLMPEL PMNMKEEAAD  420
VEYVQKRSSP TTEPELMLNN RVYTCNNGQC PQSDYGYGFL DRNARNSHQY ACKYNDPLPP  480
TVAVENKPRP PPAQQVFPTA YNQPNQALNN LDLDFSVPMD GHRSITELMN MYDNMANKST  540
SSNDDVTIIE RPNALAPRMQ MDEGFFGQGN GIGGNGGGLF DDVGNMMHQQ QQQPQAQAPQ  600
QFFIRDDTQF GNQMGNITGS SDFRFGSGFN MSGAVDYPQQ KNDGPNWYY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A3e-732133441132Protein ETHYLENE INSENSITIVE 3
4zds_B3e-732133441132Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapBrast02G164500.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2483110.0AK248311.1 Hordeum vulgare subsp. vulgare cDNA clone: FLbaf51m23, mRNA sequence.
GenBankAK3638910.0AK363891.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2019M20.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003558012.10.0ETHYLENE INSENSITIVE 3-like 1 protein
RefseqXP_010228682.10.0ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M410.0EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLI1H5Z20.0I1H5Z2_BRADI; Uncharacterized protein
STRINGBRADI1G63780.10.0(Brachypodium distachyon)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP63838168
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G20770.11e-161EIL family protein
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]