PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bv7_170910_tctt.t1
Organism
Beta vulgaris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Betoideae; Beta
Family E2F/DP
Protein Properties Length: 454aa    MW: 50574.1 Da    PI: 4.5014
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bv7_170910_tctt.t1genomeTBVRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.61.8e-27135200171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Bv7_170910_tctt.t1 135 RYDSSLGLLTKKFINLIKHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 200
                         6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.0E-29133202IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.2E-35135200IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.35E-17135198IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.5E-24137200IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.19E-47211317No hitNo description
SuperFamilySSF1440747.85E-34213317No hitNo description
PfamPF164211.6E-33216315IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 454 aa     Download sequence    Send to blast
MSTNQQSQQQ QSQQQKRQLP FTSMKPPFVP PPGDYHRFSD NRSIPPPNHS EAILVKTPPM  60
KRKSDAPEYD AESSDWTTSP GYTEIVNSPL QTPVSGKAGK GRGSRISKSN RAGPQTPVSN  120
VGSPGNSLTP VGPCRYDSSL GLLTKKFINL IKHAEDGILD LNKAADTLEV QKRRIYDITN  180
VLEGIGLIEK KLKNRIQWKG LDVSRPGEVD DSVTSLQTDV ESLSMEERRL DEQIREMQER  240
LREMSEEENN QKWLFVTEED IKGLPCFQNE TLIAIKAPHG TTLEVPDPDE AVDFPQRRYR  300
IVLRSTMGPI DVYLVSQFEE KFEEISGAEP SSSIPSTSGY DEHTAAAAKD ENQHDEIEME  360
GQETHRICSD ANAQQDFVSG IMKIVPEVDS DADYWLLSDG DVSITDMWRT DSGVEWNELG  420
TIHEDYPVAS VGTPQPQSPP PSATEVLPPN TTGR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-26130201274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ2788840.0AJ278884.1 Chenopodium rubrum mRNA for transcription factor (E2F gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010685421.10.0PREDICTED: transcription factor E2FB
SwissprotQ9FV711e-157E2FB_ARATH; Transcription factor E2FB
TrEMBLQ9FNS00.0Q9FNS0_OXYRB; Transcription factor (E2F)
STRINGXP_010685421.10.0(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-157E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]