PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Bv9_205910_kzzy.t1

Organism

Beta vulgaris

Taxonomic ID

161934

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Betoideae; Beta

Family

bHLH

Protein Properties

Length: 344aa MW: 38515.9 Da PI: 4.6448

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Bv9_205910_kzzy.t1	genome	TBVR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.7	2.7e-10	164	207	7	55
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 + Er+RR r+++++ Lr l+P+ +K++Ka+i+ Av Y+++Lq Bv9_205910_kzzy.t1 164 ISERKRRGRMKEKLYALRALVPNI-----TKMDKASIVGDAVLYVQDLQ 207 67*******************7.....7****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.805	157	206	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.9E-15	159	224	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.40E-11	159	209	No hit	No description
SuperFamily	SSF47459	3.27E-15	159	225	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.1E-12	163	212	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	6.0E-8	164	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0034756	Biological Process	regulation of iron ion transport
GO:0071281	Biological Process	cellular response to iron ion
GO:0071369	Biological Process	cellular response to ethylene stimulus
GO:0071732	Biological Process	cellular response to nitric oxide
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 344 aa Download sequence Send to blast
MDDSNSSANA TPSIPLITDF NLDFVEQNSL NFNHVIEMLR GSEISDPSAI CINQNFDPLA 60 FTRNNVSDNY SINNFYPIIS QENHVFNNFN SPTMSCTNNN TILNSSVSGF DDETIRGGGG 120 DEDDDNDDDD DNYMDGEHSS ATTNNKGSCT SSKKGKMDRS RTLISERKRR GRMKEKLYAL 180 RALVPNITKM DKASIVGDAV LYVQDLQMQS KKLRSQIDGL ENSLIAAERC QGFGDTPNKN 240 SSQNHFLPVC KMIMQMDVLQ IEDREFYAKV VSNKGQGVAA SLYKALDSLT TFVIRNSSLS 300 TLYEQFVLTF TLNVAKCRED FNLPNMKVWI SGAFLNQGFE FQSF

Sequence ? help Back to Top

Protein Sequence Length: 344 aa Download sequence Send to blast

MDDSNSSANA TPSIPLITDF NLDFVEQNSL NFNHVIEMLR GSEISDPSAI CINQNFDPLA  60
FTRNNVSDNY SINNFYPIIS QENHVFNNFN SPTMSCTNNN TILNSSVSGF DDETIRGGGG  120
DEDDDNDDDD DNYMDGEHSS ATTNNKGSCT SSKKGKMDRS RTLISERKRR GRMKEKLYAL  180
RALVPNITKM DKASIVGDAV LYVQDLQMQS KKLRSQIDGL ENSLIAAERC QGFGDTPNKN  240
SSQNHFLPVC KMIMQMDVLQ IEDREFYAKV VSNKGQGVAA SLYKALDSLT TFVIRNSSLS  300
TLYEQFVLTF TLNVAKCRED FNLPNMKVWI SGAFLNQGFE FQSF

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Essential protein involved in iron uptake responses. Regulates FRO2 at the level of mRNA accumulation and IRT1 at the level of protein accumulation. Confers enhanced iron mobilization responses at low iron supply. {ECO:0000269\|PubMed:15539473, ECO:0000269\|PubMed:15556641, ECO:0000269\|PubMed:16117851}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: In roots by iron deficiency. Repressed by cytokinins. Induced by cold, UV, ethylene (ACC), jasmonic acid (JA), flagellin, and salicylic acid (SA) treatments. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:15531708, ECO:0000269\|PubMed:15539473, ECO:0000269\|PubMed:15556641, ECO:0000269\|PubMed:18397377}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010689160.1	0.0	PREDICTED: transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR
Swissprot	Q0V7X4	1e-76	FIT_ARATH; Transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR
TrEMBL	A0A0K9RZ49	1e-104	A0A0K9RZ49_SPIOL; Uncharacterized protein
STRING	XP_010689160.1	0.0	(Beta vulgaris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G28160.1	4e-73	FER-like regulator of iron uptake

Publications ? help Back to Top
Schmid NB, et al. Feruloyl-CoA 6'-Hydroxylase1-dependent coumarins mediate iron acquisition from alkaline substrates in Arabidopsis. Plant Physiol., 2014. 164(1): p. 160-72 [PMID:24246380] Doustaly F, et al. Uranium perturbs signaling and iron uptake response in Arabidopsis thaliana roots. Metallomics, 2014. 6(4): p. 809-21 [PMID:24549117] Le CT, et al. ZINC FINGER OF ARABIDOPSIS THALIANA12 (ZAT12) Interacts with FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT) Linking Iron Deficiency and Oxidative Stress Responses. Plant Physiol., 2016. 170(1): p. 540-57 [PMID:26556796] Yang L, et al. Carbon Monoxide Interacts with Auxin and Nitric Oxide to Cope with Iron Deficiency in Arabidopsis. Front Plant Sci, 2016. 7: p. 112 [PMID:27014280] Zhou C, et al. Paenibacillus polymyxa BFKC01 enhances plant iron absorption via improved root systems and activated iron acquisition mechanisms. Plant Physiol. Biochem., 2016. 105: p. 162-173 [PMID:27105423] Mai HJ,Pateyron S,Bauer P Iron homeostasis in Arabidopsis thaliana: transcriptomic analyses reveal novel FIT-regulated genes, iron deficiency marker genes and functional gene networks. BMC Plant Biol., 2016. 16(1): p. 211 [PMID:27716045] Zhou C, et al. Exogenous Melatonin Improves Plant Iron Deficiency Tolerance via Increased Accumulation of Polyamine-Mediated Nitric Oxide. Int J Mol Sci, 2017. [PMID:27792144] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Naranjo-Arcos MA, et al. Dissection of iron signaling and iron accumulation by overexpression of subgroup Ib bHLH039 protein. Sci Rep, 2017. 7(1): p. 10911 [PMID:28883478] Kailasam S,Wang Y,Lo JC,Chang HF,Yeh KC S-Nitrosoglutathione works downstream of nitric oxide to mediate iron-deficiency signaling in Arabidopsis. Plant J., 2018. 94(1): p. 157-168 [PMID:29396986] Cui Y, et al. Four IVa bHLH Transcription Factors Are Novel Interactors of FIT and Mediate JA Inhibition of Iron Uptake in Arabidopsis. Mol Plant, 2018. 11(9): p. 1166-1183 [PMID:29960107]