PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

C.cajan_04448

Common Name

KK1_004558

Organism

Cajanus cajan

Taxonomic ID

3821

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Cajanus

Family

WRKY

Protein Properties

Length: 478aa MW: 51578.3 Da PI: 6.9915

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
C.cajan_04448	genome	IIPG	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.8	1.4e-30	229	287	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 +Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+a+d +++++tYeg+Hnh+ C.cajan_04448 229 SDGCQWRKYGQKMAKGNPCPRAYYRCTMAvGCPVRKQVQRCADDRTILTTTYEGTHNHP 287 7*********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	4.5E-33	213	289	IPR003657	WRKY domain
SuperFamily	SSF118290	8.76E-28	221	289	IPR003657	WRKY domain
PROSITE profile	PS50811	28.977	223	289	IPR003657	WRKY domain
SMART	SM00774	4.4E-36	228	288	IPR003657	WRKY domain
Pfam	PF03106	1.2E-26	230	287	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 478 aa Download sequence Send to blast
MFPTLGFPNL SPSHDHNRTV LAELDFLSAT NNSSFQPLHT NQISSHHLHV NTGLQLLTAN 60 AGSDHSTVDD GTSSEAEDKR GKIPELAQLQ EDLRRMDAEN QKLKEMLSHV SSNYANLQTH 120 VAALLQQQRM EQEVVKVKDE EKNHGGNVPR QFLDLGPSGT TEVDDQVSNS SSGERTRSST 180 PPNNKDKKET DPDTEKLNSS NTTDTSTPEA TMRKARVSVR ARSEAPMISD GCQWRKYGQK 240 MAKGNPCPRA YYRCTMAVGC PVRKQVQRCA DDRTILTTTY EGTHNHPLPP AAMAMASTTA 300 AAASMLLSGS MSSVDGIMSP NLLTRAILPC SNMATLSASA PFPTVTLDLT HNPNALQYQR 360 PQIPFPSQPQ NFVSAPTQAQ LPQLIAQALY NQSKFSGLQL SNDVGPNNSQ APRPSLQPNQ 420 QVSLADTVSA ITADPNFTAA LATAITSIIG GSNSPNNNAN NSNNTSNPNV INSATIIK

Sequence ? help Back to Top

Protein Sequence Length: 478 aa Download sequence Send to blast

MFPTLGFPNL SPSHDHNRTV LAELDFLSAT NNSSFQPLHT NQISSHHLHV NTGLQLLTAN  60
AGSDHSTVDD GTSSEAEDKR GKIPELAQLQ EDLRRMDAEN QKLKEMLSHV SSNYANLQTH  120
VAALLQQQRM EQEVVKVKDE EKNHGGNVPR QFLDLGPSGT TEVDDQVSNS SSGERTRSST  180
PPNNKDKKET DPDTEKLNSS NTTDTSTPEA TMRKARVSVR ARSEAPMISD GCQWRKYGQK  240
MAKGNPCPRA YYRCTMAVGC PVRKQVQRCA DDRTILTTTY EGTHNHPLPP AAMAMASTTA  300
AAASMLLSGS MSSVDGIMSP NLLTRAILPC SNMATLSASA PFPTVTLDLT HNPNALQYQR  360
PQIPFPSQPQ NFVSAPTQAQ LPQLIAQALY NQSKFSGLQL SNDVGPNNSQ APRPSLQPNQ  420
QVSLADTVSA ITADPNFTAA LATAITSIIG GSNSPNNNAN NSNNTSNPNV INSATIIK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	4e-21	215	291	1	76	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	C.cajan_04448

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EU019573	0.0	EU019573.1 Glycine max WRKY34 (WRKY34) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020227895.1	0.0	WRKY transcription factor 6
Swissprot	Q9C519	1e-141	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A151STV3	0.0	A0A151STV3_CAJCA; WRKY transcription factor 6
STRING	GLYMA07G39250.2	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF866	34	121

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	1e-104	WRKY family protein

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]