PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

C.cajan_12003

Common Name

KK1_012372

Organism

Cajanus cajan

Taxonomic ID

3821

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Cajanus

Family

Protein Properties

Length: 338aa MW: 38179.6 Da PI: 9.4004

Description

B3 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
C.cajan_12003	genome	IIPG	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	30.8	5.2e-10	99	146	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq C.cajan_12003 99 SHSLAERVRREKISERMKYLQDLVPGC----NKIAGKAGMLDEIINYVQSLQ 146 8************************....999***************9 PP
2	B3	50.9	2.8e-16	276	331	27	83
---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEE CS B3 27 ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFk 83 +++ + s++l+ +d++g +W++++iyr++++r++lt+GW+ Fv++++L +gD v+F C.cajan_12003 276 KQQ-RPSQELVAKDLHGVEWKFRHIYRGQPRRHLLTTGWSIFVNQKNLVSGDAVLFL 331 333.34679**********************************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.57E-16	93	164	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.79E-9	93	150	No hit	No description
PROSITE profile	PS50888	15.091	95	145	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.8E-17	97	162	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.9E-7	99	146	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.0E-9	101	151	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50863	10.377	251	338	IPR003340	B3 DNA binding domain
SMART	SM01019	0.0013	253	338	IPR003340	B3 DNA binding domain
Gene3D	G3DSA:2.40.330.10	4.4E-20	270	332	IPR015300	DNA-binding pseudobarrel domain
SuperFamily	SSF101936	1.31E-20	273	333	IPR015300	DNA-binding pseudobarrel domain
Pfam	PF02362	6.7E-14	275	331	IPR003340	B3 DNA binding domain
CDD	cd10017	3.51E-12	279	338	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009637	Biological Process	response to blue light
GO:0009911	Biological Process	positive regulation of flower development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 338 aa Download sequence Send to blast
MLHCLNTSGN IDTTLLERQK CHQPHFSATE LNAVFSSKKR KAETNCKSKV DKRLKVSARE 60 QENNNNGTTS ADTSKGSEVQ NQKPQYIHVR ARRGHATDSH SLAERVRREK ISERMKYLQD 120 LVPGCNKIAG KAGMLDEIIN YVQSLQRQVE FLSMKLAAVN PRLDFNIDEL FAKEVFPSCA 180 QSFPNIEMAS DVTNNPAYLQ FNSSQQLVSC CGGLINNMGI SPANLGIRRN ISTNTTTTIP 240 VPLLPETSFD SSCFANVLVI LIISVLQIDL NYVDYKQQRP SQELVAKDLH GVEWKFRHIY 300 RGQPRRHLLT TGWSIFVNQK NLVSGDAVLF LRCVYMFK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldv_A	3e-23	270	332	150	212	Auxin response factor 1
4ldw_A	3e-23	270	332	150	212	Auxin response factor 1
4ldw_B	3e-23	270	332	150	212	Auxin response factor 1
4ldx_A	3e-23	270	332	150	212	Auxin response factor 1
4ldx_B	3e-23	270	332	150	212	Auxin response factor 1
4ldy_A	3e-23	270	332	150	212	Auxin response factor 1
4ldy_B	3e-23	270	332	150	212	Auxin response factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds DNA to G box 5'-CACGTG-3' and, to a lower extent, to E-box 5'-CANNTG-3' in vitro. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. {ECO:0000269\|PubMed:18988809, ECO:0000269\|PubMed:24130508}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	C.cajan_12003

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Accumulates strongly in response to blue light due to reduced preventing 26S proteasome-mediated degradation in an ADO1/ZTL and ADO2/LKP2 dependent manner, but levels decrease in the absence of blue light via 26S proteasome degradation (at protein level). {ECO:0000269\|PubMed:24101505}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT098303	1e-147	BT098303.1 Soybean clone JCVI-FLGm-23G1 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020217644.1	0.0	transcription factor bHLH63
Swissprot	Q8GY61	1e-52	BH063_ARATH; Transcription factor bHLH63
TrEMBL	A0A151TGC4	0.0	A0A151TGC4_CAJCA; Transcription factor bHLH63
STRING	GLYMA11G12450.3	1e-111	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3618	34	63

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G34530.1	7e-55	cryptochrome-interacting basic-helix-loop-helix 1

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Yang D,Zhao W,Meng Y,Li H,Liu B A CIB1-LIKE transcription factor GmCIL10 from soybean positively regulates plant flowering. Sci China Life Sci, 2015. 58(3): p. 261-9 [PMID:25651969] Katsura Y, et al. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015. 5: p. 14589 [PMID:26423353] Taslimi A, et al. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat. Chem. Biol., 2016. 12(6): p. 425-30 [PMID:27065233] Liu Q, et al. The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases. Plant Cell Physiol., 2016. 57(10): p. 2175-2186 [PMID:27516416] Pathak GP, et al. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res., 2017. 45(20): p. e167 [PMID:28431041] Duan L, et al. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017. 8(1): p. 547 [PMID:28916751] Quejada JR, et al. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res., 2017. 45(20): p. e172 [PMID:29040770] Liu Y, et al. CIB1 and CO interact to mediate CRY2-dependent regulation of flowering. EMBO Rep., 2019. [PMID:30126927]