PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID C.cajan_18827
Common NameKK1_019373
Organism
Cajanus cajan
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Cajanus
Family E2F/DP
Protein Properties Length: 348aa    MW: 39560.5 Da    PI: 5.0139
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
C.cajan_18827genomeIIPGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP856e-2777142171
        E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                    r+++sL+llt+kf++l++ +++g+++ln+ a+ L   +v  ++RRiYDi+NVLe+++liek++kn+i+wkg
  C.cajan_18827  77 RYDSSLGLLTKKFVSLIQDAKDGTLDLNKTAEIL---EV--QKRRIYDITNVLEGVGLIEKTSKNHIQWKG 142
                    6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.7E-2974143IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.17E-1777140IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.4E-3577142IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.3E-2579142IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146606.25E-36153260No hitNo description
SuperFamilySSF1440743.14E-26153260No hitNo description
PfamPF164215.7E-25158257IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 348 aa     Download sequence    Send to blast
MQSSQRYELN NFKSHISNIE VAPGMITTVN LPPASVRTEP SIRGKHNGKT KASKNAKSGT  60
QRPTADSPNL TAVNNCRYDS SLGLLTKKFV SLIQDAKDGT LDLNKTAEIL EVQKRRIYDI  120
TNVLEGVGLI EKTSKNHIQW KGCDGHGPRE LGDQVNSLKA EVESLYAEEC ELDDCIRKKQ  180
ELLRDLEEKE SSQKYLFLTK EDILSLPCFQ NQEIIAIKAP KASFIEVPDP DEELGFRQRQ  240
YKMIVRSATG PIYLYLLSKD DRKFEDDSVK RVKLMDPSWN RDHYRNMGVE LLESQDDEKN  300
PSENFSLQGS QAFGIQEIAH TGFEMEDDYW FQSDPGVSLT ELWGTNIF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-2576143674PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapC.cajan_18827
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0970030.0BT097003.1 Soybean clone JCVI-FLGm-15J6 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020219895.10.0transcription factor E2FC isoform X1
SwissprotQ9FV703e-90E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A151TCJ90.0A0A151TCJ9_CAJCA; Transcription factor E2F4
STRINGGLYMA04G02720.40.0(Glycine max)
STRINGXP_007136084.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF118852529
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.21e-92E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]