PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CA00g07140

Organism

Capsicum annuum

Taxonomic ID

4072

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum

Family

E2F/DP

Protein Properties

Length: 475aa MW: 52206.4 Da PI: 4.5044

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CA00g07140	genome	PEP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.3	2.3e-27	149	214	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg CA00g07140 149 RYDSSLGLLTKKFINLIKHAEDGMLDLNQAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 214 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.4E-29	147	216	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.6E-34	149	214	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	2.45E-17	149	212	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	1.4E-24	151	214	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	2.88E-33	229	331	No hit	No description
Pfam	PF16421	3.8E-33	230	329	IPR032198	E2F transcription factor, CC-MB domain
CDD	cd14660	4.71E-47	230	331	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 475 aa Download sequence Send to blast
MTASFVTNED YHRFCTPWVV DSSRIDSLQP DAIVVKSPAL FVAHEDFHRF STPGVVDSSR 60 VDSLQPDAIV VKSPALKRKT GYIKEVESSI CTANSGYADV ANSPLGTPVS GKGGRAHGQL 120 RATKSNKSGP PTPAFNAGSP SPLTPASCRY DSSLGLLTKK FINLIKHAED GMLDLNQAAD 180 TLEVQKRRIY DITNVLEGIG LIEKKLKNRI QWKGVDASKP GGVDNDAAIL KANIDSLSME 240 ERRLDERIRE MQEKLRDMSE DENNQRWLFV TEDDIKSLPC FQNETLIAVK APHGTTLEVP 300 DPDEAVDYPQ RRYRIILRST MGPIDVYLVS QFEEKFEEMN GFEPSTTIPD ASSSGSKDYP 360 AVEISTVSNN VTENEGQTQN VDQLSSDVGT SQDYGGGMMK ILPSDVDDAA DYLFLSDPNV 420 SMTDMWKNDC ILVSTVWDGE SLLRDFEIDD LASPRPHTPS SNADVPAPMN IPPR*

Sequence ? help Back to Top

Protein Sequence Length: 475 aa Download sequence Send to blast

MTASFVTNED YHRFCTPWVV DSSRIDSLQP DAIVVKSPAL FVAHEDFHRF STPGVVDSSR  60
VDSLQPDAIV VKSPALKRKT GYIKEVESSI CTANSGYADV ANSPLGTPVS GKGGRAHGQL  120
RATKSNKSGP PTPAFNAGSP SPLTPASCRY DSSLGLLTKK FINLIKHAED GMLDLNQAAD  180
TLEVQKRRIY DITNVLEGIG LIEKKLKNRI QWKGVDASKP GGVDNDAAIL KANIDSLSME  240
ERRLDERIRE MQEKLRDMSE DENNQRWLFV TEDDIKSLPC FQNETLIAVK APHGTTLEVP  300
DPDEAVDYPQ RRYRIILRST MGPIDVYLVS QFEEKFEEMN GFEPSTTIPD ASSSGSKDYP  360
AVEISTVSNN VTENEGQTQN VDQLSSDVGT SQDYGGGMMK ILPSDVDDAA DYLFLSDPNV  420
SMTDMWKNDC ILVSTVWDGE SLLRDFEIDD LASPRPHTPS SNADVPAPMN IPPR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	3e-25	142	215	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC239738	7e-85	AC239738.5 Solanum lycopersicum strain Heinz 1706 chromosome 1 clone hba-240p19 map 1, complete sequence.
GenBank	HG975440	7e-85	HG975440.1 Solanum pennellii chromosome ch01, complete genome.
GenBank	HG975513	7e-85	HG975513.1 Solanum lycopersicum chromosome ch01, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016561923.1	0.0	PREDICTED: transcription factor E2FA, partial
Swissprot	Q9FNY0	1e-138	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A1U8FZY2	0.0	A0A1U8FZY2_CAPAN; transcription factor E2FA
STRING	PGSC0003DMT400042347	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-142	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]