PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CA00g63000

Organism

Capsicum annuum

Taxonomic ID

4072

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum

Family

HSF

Protein Properties

Length: 369aa MW: 42587.3 Da PI: 5.4054

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CA00g63000	genome	PEP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	109.1	3.3e-34	69	160	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Flkk++e+++d++++++isws++++sfvv+d+++f+ ++Lpk+Fkh+nf+SF+RQLn+Y F+kv++++ weF+++ F+kgkk+ll +ik CA00g63000 69 FLKKTFEMVDDPDTDSIISWSNTQTSFVVWDPHKFSIHLLPKHFKHNNFSSFIRQLNTYRFRKVDSDR---------WEFANEGFQKGKKNLLINIK 156 9**************************************************************999.........**************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k+ CA00g63000 157 RRKQ 160 97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.5E-37	65	158	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	6.53E-34	65	158	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	7.7E-54	65	158	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	7.3E-18	69	92	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	2.4E-30	69	158	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	7.3E-18	107	119	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	108	132	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	7.3E-18	120	132	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 369 aa Download sequence Send to blast
MELETMGDQK TMVIDVKEKQ KINGLLEVKE DLVLFLDEDD IIGSVAADGN FTSLPKPLEG 60 LRDVGPPPFL KKTFEMVDDP DTDSIISWSN TQTSFVVWDP HKFSIHLLPK HFKHNNFSSF 120 IRQLNTYRFR KVDSDRWEFA NEGFQKGKKN LLINIKRRKQ YSQQGGSAKS WLGSCKDGGT 180 DQAEIEKLKK DQNTLKMEIL RLKQQQESTD SYLATMKERL QNTETRQKYM VIFMAKIFKN 240 PLFVQHLVEK MKQGKTLDNG RFTKKRRLTN ATTDGDEKSL QFQEEYTTIK SEIQTLFSSD 300 DSSGPVEEQK AKGNNSPDIL PENYILWEKL MEDDMICENG EETDKYQSEI VHELEDLISK 360 PSELKCMP*

Sequence ? help Back to Top

Protein Sequence Length: 369 aa Download sequence Send to blast

MELETMGDQK TMVIDVKEKQ KINGLLEVKE DLVLFLDEDD IIGSVAADGN FTSLPKPLEG  60
LRDVGPPPFL KKTFEMVDDP DTDSIISWSN TQTSFVVWDP HKFSIHLLPK HFKHNNFSSF  120
IRQLNTYRFR KVDSDRWEFA NEGFQKGKKN LLINIKRRKQ YSQQGGSAKS WLGSCKDGGT  180
DQAEIEKLKK DQNTLKMEIL RLKQQQESTD SYLATMKERL QNTETRQKYM VIFMAKIFKN  240
PLFVQHLVEK MKQGKTLDNG RFTKKRRLTN ATTDGDEKSL QFQEEYTTIK SEIQTLFSSD  300
DSSGPVEEQK AKGNNSPDIL PENYILWEKL MEDDMICENG EETDKYQSEI VHELEDLISK  360
PSELKCMP*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	1e-22	67	158	27	129	Heat shock factor protein 1
5d5v_B	1e-22	67	158	27	129	Heat shock factor protein 1
5d5v_D	1e-22	67	158	27	129	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat stress, high light and hydrogen peroxide (H(2)O(2)). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016580278.1	0.0	PREDICTED: heat stress transcription factor A-2-like
Swissprot	O80982	3e-81	HSFA2_ARATH; Heat stress transcription factor A-2
TrEMBL	A0A2G2Z2K5	0.0	A0A2G2Z2K5_CAPAN; Heat stress transcription factor A-2e
STRING	PGSC0003DMT400082752	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5681	22	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G26150.1	1e-83	heat shock transcription factor A2

Publications ? help Back to Top
Liu HC,Charng YY Common and distinct functions of Arabidopsis class A1 and A2 heat shock factors in diverse abiotic stress responses and development. Plant Physiol., 2013. 163(1): p. 276-90 [PMID:23832625] Jung HS, et al. Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9 [PMID:23918368] Chauhan H,Khurana N,Agarwal P,Khurana JP,Khurana P A seed preferential heat shock transcription factor from wheat provides abiotic stress tolerance and yield enhancement in transgenic Arabidopsis under heat stress environment. PLoS ONE, 2013. 8(11): p. e79577 [PMID:24265778] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Weng M, et al. Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Plant Cell Environ., 2014. 37(9): p. 2128-38 [PMID:24548003] Jang YH, et al. A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana. Plant J., 2014. 78(4): p. 591-603 [PMID:24580679] Stief A, et al. Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors. Plant Cell, 2014. 26(4): p. 1792-1807 [PMID:24769482] Dobrá J, et al. The impact of heat stress targeting on the hormonal and transcriptomic response in Arabidopsis. Plant Sci., 2015. 231: p. 52-61 [PMID:25575991] Yamauchi Y,Kunishima M,Mizutani M,Sugimoto Y Reactive short-chain leaf volatiles act as powerful inducers of abiotic stress-related gene expression. Sci Rep, 2015. 5: p. 8030 [PMID:25619826] Shi H, et al. Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis. J. Pineal Res., 2015. 58(3): p. 335-42 [PMID:25711624] Mueller SP,Krause DM,Mueller MJ,Fekete A Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation. J. Exp. Bot., 2015. 66(15): p. 4517-26 [PMID:25977236] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Hu Z, et al. Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis. Plant J., 2015. 84(6): p. 1178-91 [PMID:26576681] Lämke J,Brzezinka K,Bäurle I HSFA2 orchestrates transcriptional dynamics after heat stress in Arabidopsis thaliana. Transcription, 2016. 7(4): p. 111-4 [PMID:27383578] Wang X,Huang W,Liu J,Yang Z,Huang B Molecular regulation and physiological functions of a novel FaHsfA2c cloned from tall fescue conferring plant tolerance to heat stress. Plant Biotechnol. J., 2017. 15(2): p. 237-248 [PMID:27500592] Chen ST,He NY,Chen JH,Guo FQ Identification of core subunits of photosystem II as action sites of HSP21, which is activated by the GUN5-mediated retrograde pathway in Arabidopsis. Plant J., 2017. 89(6): p. 1106-1118 [PMID:27943531] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Wang X,Zhuang L,Shi Y,Huang B Up-Regulation of HSFA2c and HSPs by ABA Contributing to Improved Heat Tolerance in Tall Fescue and Arabidopsis. Int J Mol Sci, 2018. [PMID:28914758] Llamas E,Pulido P,Rodriguez-Concepcion M Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis. PLoS Genet., 2017. 13(9): p. e1007022 [PMID:28937985] Li X, et al. Plastid Translation Elongation Factor Tu Is Prone to Heat-Induced Aggregation Despite Its Critical Role in Plant Heat Tolerance. Plant Physiol., 2018. 176(4): p. 3027-3045 [PMID:29444814]