PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CA03g01440

Organism

Capsicum annuum

Taxonomic ID

4072

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum

Family

bHLH

Protein Properties

Length: 286aa MW: 32875.2 Da PI: 5.8897

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CA03g01440	genome	PEP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	38.6	1.9e-12	86	137	1	55
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +r+ h e+Er+RR+++N ++ L++l+P++ + ++ + a+i+ A+e++++L+ CA03g01440 86 QRMIHIEVERNRRKQMNAHLHVLKSLMPSS---YVQRGDQASIVGGAIEFVRELE 137 6999************************...9***************9995 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	3.47E-11	84	141	No hit	No description
SuperFamily	SSF47459	8.77E-16	84	159	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	14.335	85	136	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.1E-12	85	140	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.3E-10	86	137	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.9E-9	91	142	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF55021	2.49E-5	208	275	No hit	No description
CDD	cd04873	0.0035	211	275	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 286 aa Download sequence Send to blast
MPTIYDNYYS LNEDPYCHNY QHPPMVDEEV ALMVPQKEDK FKEEINASSQ VSFHGDNVEN 60 RKANESKKKK RKRITRIKSS EEVENQRMIH IEVERNRRKQ MNAHLHVLKS LMPSSYVQRG 120 DQASIVGGAI EFVRELEQLL QCLESQKRRK LNGDDEYSSL MDIQDPQLLF APNNNLPLTN 180 ENEIEMQEDR AEIKSCLADV EVKIIGSDNA IIKILSKRRP GQLINTISAL QDLQLNIIHT 240 NVTTIEETVL YSFNVKICGE TRFTADNIAN LVQQIFSFFH ANSPL*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	66	71	KKKKRK
2	66	72	KKKKRKR
3	86	97	RMIHIEVERNRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269\|PubMed:17088607, ECO:0000269\|PubMed:17183265, ECO:0000269\|PubMed:17183267, ECO:0000269\|PubMed:24571519, ECO:0000269\|PubMed:24654956}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269\|PubMed:22442411}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975448	2e-77	HG975448.1 Solanum pennellii chromosome ch09, complete genome.
GenBank	HG975521	2e-77	HG975521.1 Solanum lycopersicum chromosome ch09, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016555209.1	0.0	PREDICTED: transcription factor FAMA-like
Swissprot	Q56YJ8	3e-90	FAMA_ARATH; Transcription factor FAMA
TrEMBL	A0A1U8FFW1	0.0	A0A1U8FFW1_CAPAN; Transcription factor FAMA
TrEMBL	A0A2G2ZTP6	0.0	A0A2G2ZTP6_CAPAN; transcription factor FAMA-like
STRING	PGSC0003DMT400076223	1e-137	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4657	23	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G24140.1	2e-73	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Matos JL, et al. Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module. Elife, 2015. [PMID:25303364] Chen L, et al. NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis. Development, 2016. 143(9): p. 1600-11 [PMID:26989174] Lee JH,Jung JH,Park CM Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis. Plant Cell, 2017. 29(11): p. 2817-2830 [PMID:29070509] Han X, et al. Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons. Plant Physiol., 2018. 176(4): p. 2871-2885 [PMID:29496884] Li X,Yang R,Chen H The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA. PLoS ONE, 2018. 13(3): p. e0193458 [PMID:29513733]