PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CCG005686.1

Organism

Populus euphratica

Taxonomic ID

75702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

E2F/DP

Protein Properties

Length: 457aa MW: 49952.9 Da PI: 4.8846

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CCG005686.1	genome	LZU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	84.8	6.7e-27	146	211	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt++f++l++++++gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+irwkg CCG005686.1 146 RYDSSLGLLTKRFVDLFKHADDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 211 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.3E-28	143	213	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	4.08E-17	146	209	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	3.5E-34	146	211	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	5.0E-24	148	211	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	1.1E-30	225	328	No hit	No description
CDD	cd14660	5.19E-47	227	328	No hit	No description
Pfam	PF16421	3.6E-32	227	326	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 457 aa Download sequence Send to blast
MSGSAKASTR PAAQPPPSGP IQPPLTRQLA FATMKPSFVP PDDYHRFSSP STSRVTADRD 60 AEAIVVRSPQ LKRKSALDDN GVGSSNRASS PGSTSISNIP FRTPVSAKAG RTYNKSKASK 120 GSGAGPQTPV SKADCASPLT PAGSCRYDSS LGLLTKRFVD LFKHADDGIL DLNNAAETLE 180 VQKRRIYDIT NVLEGIGLIE KTLKNRIRWK GIDASRPGQV EGDATLLQAE IAKLTMEELT 240 LDDQIREMQE RLRDLSEDEN NQKRLFVTEE DIKSLPCFLN ETLIAIKAPH GTTLEVPDPD 300 EAVDYPQRRY RIILRSSMGP IDVYLVSQFE ENFEEMNNVE TSVSIPLASI SASHGNPMTE 360 MTTDVRTQGR SGSLAQQAQT MFSDPNTTQE LGGMMKIVPS DVHDDSDYWL LSDAGISITD 420 MWKTDSNTEW ADFGVTDVQT PRTQTPLHGI TEVPPGV

Sequence ? help Back to Top

Protein Sequence Length: 457 aa Download sequence Send to blast

MSGSAKASTR PAAQPPPSGP IQPPLTRQLA FATMKPSFVP PDDYHRFSSP STSRVTADRD  60
AEAIVVRSPQ LKRKSALDDN GVGSSNRASS PGSTSISNIP FRTPVSAKAG RTYNKSKASK  120
GSGAGPQTPV SKADCASPLT PAGSCRYDSS LGLLTKRFVD LFKHADDGIL DLNNAAETLE  180
VQKRRIYDIT NVLEGIGLIE KTLKNRIRWK GIDASRPGQV EGDATLLQAE IAKLTMEELT  240
LDDQIREMQE RLRDLSEDEN NQKRLFVTEE DIKSLPCFLN ETLIAIKAPH GTTLEVPDPD  300
EAVDYPQRRY RIILRSSMGP IDVYLVSQFE ENFEEMNNVE TSVSIPLASI SASHGNPMTE  360
MTTDVRTQGR SGSLAQQAQT MFSDPNTTQE LGGMMKIVPS DVHDDSDYWL LSDAGISITD  420
MWKTDSNTEW ADFGVTDVQT PRTQTPLHGI TEVPPGV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-23	141	212	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011046879.1	0.0	PREDICTED: transcription factor E2FA-like
Swissprot	Q9FNY0	1e-157	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A2K2A5E0	0.0	A0A2K2A5E0_POPTR; Uncharacterized protein
STRING	POPTR_0006s22150.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1947	34	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-153	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]