PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CCG009193.1

Organism

Populus euphratica

Taxonomic ID

75702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

AP2

Protein Properties

Length: 530aa MW: 59151.1 Da PI: 7.286

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CCG009193.1	genome	LZU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	53.3	6.9e-17	173	222	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g CCG009193.1 173 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 222 78*****************......55**********************997 PP
2	AP2	43.7	6.8e-14	265	315	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g CCG009193.1 265 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEIEAARAYDKAAIKCNG 315 89******.7**5553..2.26******99********99776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	2.03E-15	173	231	IPR016177	DNA-binding domain
Pfam	PF00847	6.3E-9	173	222	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.53	174	230	IPR001471	AP2/ERF domain
CDD	cd00018	2.13E-11	174	231	No hit	No description
SMART	SM00380	2.1E-31	174	236	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.0E-16	174	230	IPR001471	AP2/ERF domain
CDD	cd00018	4.36E-25	265	325	No hit	No description
Pfam	PF00847	1.4E-9	265	315	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.28E-17	265	325	IPR016177	DNA-binding domain
PROSITE profile	PS51032	15.461	266	323	IPR001471	AP2/ERF domain
SMART	SM00380	4.2E-31	266	329	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.4E-16	266	323	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.2E-6	267	278	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.2E-6	305	325	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 530 aa Download sequence Send to blast
MWNLNDSPDQ TRDDESEGCS SQKTSIDGED DKGKRVGSVS NSSSSAAVFE DGSEEEDAVG 60 EKGNKIIKKR SISISSSSSK IFGFSVPYDQ YSMDMSDPPV TRQFFPLEDQ EMGSTSGVGG 120 SFGGGDGVGG GFPRAHWVGV KFCQSESSLA SQKSMEVSQP LKKSRRGPRS RSSQYRGVTF 180 YRRTGRWESH IWDCGKQVYL GGFDTAHAAA RAYDRAAIKF RGVEADINFR IEDYEEDLKQ 240 MSNLTKEEFV HVLRRQSTGF PRGSSKYRGV TLHKCGRWEA RMGQFLGKKY VYLGLFDTEI 300 EAARAYDKAA IKCNGKEAVT NFDPSIYENE HSIESQGNAA DHNLDLSLGN PASKQIEFGQ 360 DRHSVAMEQH SATMPFEPNW QNRGLRPRQL NLCTSDNDGH GRDGYGETET TQLLSKIHIQ 420 SPASLKSSEM PRYEQFRRSL GDSQIHPFLP PQFNPPNYQT QHPSSSNGGR IGSDLSLTPS 480 ELHYHHHYQQ WQAGPPRFAN AAASSGFQQQ IRTPQNWLQK NGFNSLMRPS

Sequence ? help Back to Top

Protein Sequence Length: 530 aa Download sequence Send to blast

MWNLNDSPDQ TRDDESEGCS SQKTSIDGED DKGKRVGSVS NSSSSAAVFE DGSEEEDAVG  60
EKGNKIIKKR SISISSSSSK IFGFSVPYDQ YSMDMSDPPV TRQFFPLEDQ EMGSTSGVGG  120
SFGGGDGVGG GFPRAHWVGV KFCQSESSLA SQKSMEVSQP LKKSRRGPRS RSSQYRGVTF  180
YRRTGRWESH IWDCGKQVYL GGFDTAHAAA RAYDRAAIKF RGVEADINFR IEDYEEDLKQ  240
MSNLTKEEFV HVLRRQSTGF PRGSSKYRGV TLHKCGRWEA RMGQFLGKKY VYLGLFDTEI  300
EAARAYDKAA IKCNGKEAVT NFDPSIYENE HSIESQGNAA DHNLDLSLGN PASKQIEFGQ  360
DRHSVAMEQH SATMPFEPNW QNRGLRPRQL NLCTSDNDGH GRDGYGETET TQLLSKIHIQ  420
SPASLKSSEM PRYEQFRRSL GDSQIHPFLP PQFNPPNYQT QHPSSSNGGR IGSDLSLTPS  480
ELHYHHHYQQ WQAGPPRFAN AAASSGFQQQ IRTPQNWLQK NGFNSLMRPS

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269\|PubMed:1675158, ECO:0000269\|PubMed:23034631, ECO:0000269\|PubMed:7919989}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:12893888, ECO:0000269\|PubMed:14555699}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KC477295	0.0	KC477295.1 Populus tomentosa AP2-1 gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011043502.1	0.0	PREDICTED: floral homeotic protein APETALA 2-like isoform X1
Swissprot	P47927	1e-129	AP2_ARATH; Floral homeotic protein APETALA 2
TrEMBL	B9HH99	0.0	B9HH99_POPTR; Uncharacterized protein
STRING	POPTR_0007s10780.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3784	34	63

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36920.2	1e-121	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Thamilarasan SK,Park JI,Jung HJ,Nou IS Genome-wide analysis of the distribution of AP2/ERF transcription factors reveals duplication and CBFs genes elucidate their potential function in Brassica oleracea. BMC Genomics, 2014. 15: p. 422 [PMID:24888752] Zhang GB,Yi HY,Gong JM The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation. Plant Cell, 2014. 26(10): p. 3984-98 [PMID:25326291] Ranocha P,Francoz E,Burlat V,Dunand C Expression of PRX36, PMEI6 and SBT1.7 is controlled by complex transcription factor regulatory networks for proper seed coat mucilage extrusion. Plant Signal Behav, 2014. 9(11): p. e977734 [PMID:25531128] Djemal R,Khoudi H Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum). Protoplasma, 2015. 252(6): p. 1461-73 [PMID:25687296] Kazan K Diverse roles of jasmonates and ethylene in abiotic stress tolerance. Trends Plant Sci., 2015. 20(4): p. 219-29 [PMID:25731753] Prunet N, et al. SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signalling. J. Exp. Bot., 2015. 66(21): p. 6905-16 [PMID:26269626] Xie W, et al. Exploring potential new floral organ morphogenesis genes of Arabidopsis thaliana using systems biology approach. Front Plant Sci, 2015. 6: p. 829 [PMID:26528302] Zumajo-Cardona C,Pabón-Mora N Evolution of the APETALA2 Gene Lineage in Seed Plants. Mol. Biol. Evol., 2016. 33(7): p. 1818-32 [PMID:27030733] Zhao Y, et al. An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design. Sci Rep, 2016. 6: p. 23890 [PMID:27033976] Gao R,Liu P,Irwanto N,Loh R,Wong SM Upregulation of LINC-AP2 is negatively correlated with AP2 gene expression with Turnip crinkle virus infection in Arabidopsis thaliana. Plant Cell Rep., 2016. 35(11): p. 2257-2267 [PMID:27473526] Huang Z, et al. APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. New Phytol., 2017. 215(3): p. 1197-1209 [PMID:27604611] Dory M, et al. Kinase-Associated Phosphoisoform Assay: a novel candidate-based method to detect specific kinase-substrate phosphorylation interactions in vivo. BMC Plant Biol., 2016. 16(1): p. 204 [PMID:27655033] Wang P, et al. Expansion and Functional Divergence of AP2 Group Genes in Spermatophytes Determined by Molecular Evolution and Arabidopsis Mutant Analysis. Front Plant Sci, 2016. 7: p. 1383 [PMID:27703459] Sharma P, et al. Promoter Trapping and Deletion Analysis Show Arabidopsis thaliana APETALA2 Gene Promoter Is Bidirectional and Functions as a Pollen- and Ovule-Specific Promoter in the Reverse Orientation. Appl. Biochem. Biotechnol., 2017. 182(4): p. 1591-1604 [PMID:28130768] Kihira M, et al. Arabidopsis thaliana FLO2 is Involved in Efficiency of Photoassimilate Translocation, Which is Associated with Leaf Growth and Aging, Yield of Seeds and Seed Quality. Plant Cell Physiol., 2017. 58(3): p. 440-450 [PMID:28158741] Balanzà V, et al. Genetic control of meristem arrest and life span in Arabidopsis by a FRUITFULL-APETALA2 pathway. Nat Commun, 2018. 9(1): p. 565 [PMID:29422669] Dotto M,Gómez MS,Soto MS,Casati P UV-B radiation delays flowering time through changes in the PRC2 complex activity and miR156 levels in Arabidopsis thaliana. Plant Cell Environ., 2018. 41(6): p. 1394-1406 [PMID:29447428] Song C,Lee J,Kim T,Hong JC,Lim CO VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis. Planta, 2018. 247(6): p. 1439-1448 [PMID:29536220]