PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cagra.1390s0037.1.p
Organism
Capsella grandiflora
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family E2F/DP
Protein Properties Length: 301aa    MW: 34411.6 Da    PI: 8.5754
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cagra.1390s0037.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.12.6e-2790170171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                          rkeksL+ll+q+f+k++ +s+++ +tl+++ak+L+s+     ++++k+RR+YDi+NV++++nliek     ++k+++rw g
  Cagra.1390s0037.1.p  90 RKEKSLWLLSQNFVKMFLCSDDDLITLDSAAKALLSDsqdpvHMRTKVRRLYDIANVFSSMNLIEKthipeTKKPAYRWLG 170
                          79********************************************************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.3E-2387172IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.9E-3390170IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.4E-2091170IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.9E-1392171IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 301 aa     Download sequence    Send to blast
HFPFELIRLH TQIVARRGKN MYSWKGFGEV PRSLNELKEE GMRERLGDSS TNNSDKISHD  60
GEREEESFTF TPDDQENSSS SKIVPFSDQR KEKSLWLLSQ NFVKMFLCSD DDLITLDSAA  120
KALLSDSQDP VHMRTKVRRL YDIANVFSSM NLIEKTHIPE TKKPAYRWLG SDSIAEKGTS  180
LFNSDEPKKR VFGREITNLR AKRSKTDCSS NCKQIGYKKH DEENTEQESK PVASKYVFGP  240
FSPTGGAKRN DNVGKGRLLE IESLAASATY RPQYCNQEIT SLFGHYTEAW KKWFAELDRK  300
*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-151216259228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapCagra.1390s0037.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006297996.10.0E2F transcription factor-like E2FF
SwissprotQ8RWL01e-167E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLR0HMF00.0R0HMF0_9BRAS; Uncharacterized protein
STRINGCagra.1390s0037.1.p0.0(Capsella grandiflora)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-170DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]