PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10009520m
Common NameCARUB_v10009520mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family BES1
Protein Properties Length: 365aa    MW: 39351.6 Da    PI: 9.1761
Description BES1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10009520mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1DUF822207.15e-64491882144
           DUF822   2 gsgrkptwkErEnnkrRERrRRaiaakiyaGLRaqGnyklpkraDnneVlkALcreAGwvvedDGttyrkgskpleeaeaagssasaspesslq 95 
                      +++rkp+w+ErEnn+rRERrRRa+aakiy+GLRaqGny+lpk++DnneVlkALc eAGwvve+DGttyrkg kpl   ++agss++a+p ss +
  Carubv10009520m  49 ATRRKPSWRERENNRRRERRRRAVAAKIYTGLRAQGNYNLPKHCDNNEVLKALCSEAGWVVEEDGTTYRKGHKPL-PGDMAGSSSRATPYSSHN 141
                      689************************************************************************.****************** PP

           DUF822  96 sslkssalaspvesysaspksssfpspssldsislasaasllpvlsvls 144
                      +s+ ss++ sp+ sy+ sp+sssfpsps++   ++   ++++p+l++ +
  Carubv10009520m 142 QSPLSSTFDSPILSYQVSPSSSSFPSPSRVGDPHNI--STIFPFLRNGG 188
                      *****************************8776655..67888887765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF056873.5E-6150171IPR008540BES1/BZR1 plant transcription factor, N-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009742Biological Processbrassinosteroid mediated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005829Cellular Componentcytosol
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 365 aa     Download sequence    Send to blast
LTSHSSSPSS SSSADSSSVP TGVLRICWEG KMTSDGATST SAAAAAAMAT RRKPSWRERE  60
NNRRRERRRR AVAAKIYTGL RAQGNYNLPK HCDNNEVLKA LCSEAGWVVE EDGTTYRKGH  120
KPLPGDMAGS SSRATPYSSH NQSPLSSTFD SPILSYQVSP SSSSFPSPSR VGDPHNISTI  180
FPFLRNGGIP SSLPPLRISN SCPVTPPVSS PTSRNPKPLP TWESFTKQSM SMAAKQSMTS  240
LNYPFYAVSA PASPTHHRQF HAPATIPECD ESDSSTVDSG HWISFQKFSQ QPFHGASVVP  300
ASPTFNLVKP APQQLSPNTA ATQEIGQSSD FKFENSQVKP WEGERIHDVA MEDLELTLGN  360
GKSS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5zd4_A1e-3551133371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_B1e-3551133371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_C1e-3551133371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_D1e-3551133371453Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
15069RRKPSWRERENNRRRERRRR
Functional Description ? help Back to Top
Source Description
UniProtPositive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610). {ECO:0000269|PubMed:12007405, ECO:0000269|PubMed:15680330, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:19170933, ECO:0000269|PubMed:20139304, ECO:0000269|PubMed:24838002, ECO:0000269|PubMed:24981610}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00073ChIP-chipTransfer from AT1G19350Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10009520m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0650410.0AY065041.1 Arabidopsis thaliana At1g19350/F18O14_4 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006305153.20.0protein BRASSINAZOLE-RESISTANT 2
RefseqXP_023644976.10.0protein BRASSINAZOLE-RESISTANT 2
SwissprotQ9LN630.0BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
TrEMBLR0GQL60.0R0GQL6_9BRAS; Uncharacterized protein (Fragment)
STRINGXP_006305153.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM24722772
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G19350.30.0BES1 family protein
Publications ? help Back to Top
  1. Salazar-Henao JE,Lehner R,Betegón-Putze I,Vilarrasa-Blasi J,Caño-Delgado AI
    BES1 regulates the localization of the brassinosteroid receptor BRL3 within the provascular tissue of the Arabidopsis primary root.
    J. Exp. Bot., 2016. 67(17): p. 4951-61
    [PMID:27511026]
  2. Nolan T, et al.
    Identification of Brassinosteroid Target Genes by Chromatin Immunoprecipitation Followed by High-Throughput Sequencing (ChIP-seq) and RNA-Sequencing.
    Methods Mol. Biol., 2017. 1564: p. 63-79
    [PMID:28124247]
  3. Ye H, et al.
    RD26 mediates crosstalk between drought and brassinosteroid signalling pathways.
    Nat Commun, 2017. 8: p. 14573
    [PMID:28233777]
  4. Nolan TM, et al.
    Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival.
    Dev. Cell, 2017. 41(1): p. 33-46.e7
    [PMID:28399398]
  5. Yang M, et al.
    SINAT E3 Ligases Control the Light-Mediated Stability of the Brassinosteroid-Activated Transcription Factor BES1 in Arabidopsis.
    Dev. Cell, 2017. 41(1): p. 47-58.e4
    [PMID:28399399]
  6. Chen J, et al.
    Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses.
    Plant Cell, 2017. 29(6): p. 1425-1439
    [PMID:28576847]
  7. Yang M,Wang X
    Multiple Ways of BES1/BZR1 Degradation to Decode Distinct Developmental and Environmental Cues in Plants.
    Mol Plant, 2017. 10(7): p. 915-917
    [PMID:28629641]
  8. Saito M,Kondo Y,Fukuda H
    BES1 and BZR1 Redundantly Promote Phloem and Xylem Differentiation.
    Plant Cell Physiol., 2018. 59(3): p. 590-600
    [PMID:29385529]
  9. Liang T, et al.
    UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis.
    Dev. Cell, 2018. 44(4): p. 512-523.e5
    [PMID:29398622]