PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cc00_g35310

Common Name

GSCOC_T00007535001

Organism

Coffea canephora

Taxonomic ID

49390

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Coffeeae; Coffea

Family

E2F/DP

Protein Properties

Length: 168aa MW: 19275.3 Da PI: 9.2339

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cc00_g35310	genome	CGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	72.9	3.4e-23	29	94	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+l t++f++l++++e+gi++lne+ak+L ++ ++RRiYDi+ VL +++liek+ k+ irw g Cc00_g35310 29 RNDRSLGLQTKNFVNLIKHAEDGILDLNEAAKTL---EM--SKRRIYDITSVLGGIGLIEKELKSTIRWTG 94 789*****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.8E-24	26	95	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	9.87E-15	29	92	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	4.2E-25	29	94	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.6E-20	31	94	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	2.62E-8	99	154	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005667	Cellular Component	transcription factor complex
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 168 aa Download sequence Send to blast
MSGGNAYRSK VTPLTPLFNA KGGKARSCRN DRSLGLQTKN FVNLIKHAED GILDLNEAAK 60 TLEMSKRRIY DITSVLGGIG LIEKELKSTI RWTGLGASRQ PDLQAEVENL SMEERRLDDR 120 IRLEMQERLR DLSAINQKWL FVTFEDIKVV PCFQVLFYCF VVWQFLFS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	8e-20	28	97	6	76	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027174750.1	5e-87	transcription factor E2FA-like
Swissprot	Q9FNY0	1e-44	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A068VNG9	1e-121	A0A068VNG9_COFCA; Uncharacterized protein (Fragment)
STRING	XP_010262959.1	1e-56	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	5e-41	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]