PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ciclev10011698m
Common NameCICLE_v10011531mg
Organism
Citrus clementina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family HSF
Protein Properties Length: 454aa    MW: 51044.4 Da    PI: 5.2427
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ciclev10011698mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind109.91.8e-34711622102
                      HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXX CS
     HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkelle 95 
                      Fl+k++++++d +l+ +isw ++g+sfvv+d+ ef++ +Lp+ Fkh+nf+SFvRQLn+YgF+k+++++         weF+++ F++g+++ll+
  Ciclev10011698m  71 FLSKTFDLVDDTSLDPIISWGSTGESFVVWDPLEFSRLILPRNFKHNNFSSFVRQLNTYGFRKIDTDR---------WEFANEAFQRGRRHLLK 155
                      9****************************************************************999.........***************** PP

                      XXXXXXX CS
     HSF_DNA-bind  96 kikrkks 102
                      +i+r+ks
  Ciclev10011698m 156 NIRRRKS 162
                      *****97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467851.77E-3466160IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004151.7E-5667160IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.101.7E-3668160IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000561.6E-177194IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004472.2E-3071160IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.6E-17109121IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS004340110134IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.6E-17122134IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 454 aa     Download sequence    Send to blast
MDKEEQNYPK SPPNTAVITS SVPEATPLSM ETIAFPTTVE ELEAFSSFAT TPAADVPQPL  60
DCLHGNPIPP FLSKTFDLVD DTSLDPIISW GSTGESFVVW DPLEFSRLIL PRNFKHNNFS  120
SFVRQLNTYG FRKIDTDRWE FANEAFQRGR RHLLKNIRRR KSPQSQQIGT YIGPFSEAEK  180
SGVQGDIEQL RKERGMLMQE VVELHQQHRG TASHMEAINQ RIHAAEQRQK QMVSFLAKLL  240
QNPAFLARLK QKKEQGEIDS SRMKRKFVKH QPHELGKSDS SVEGQIVTYR PDWGNLTIPN  300
VVPESHHVPV ERSPDYLLDG MVGIGSGRED MPFQFENVAS VDLAVSDELA VPGGFTKAPE  360
QMGEGASSSG IKDPHFKEKN VMSPQQEVRS ECFVSFPQDL MKENIHDVSS PGIECIATQE  420
DIWNLGFDAT AGVSREWEQY SFGSMAYYES PLL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A3e-226816017120Heat shock factor protein 1
5d5u_B3e-226816026129Heat shock factor protein 1
5d5v_B3e-226816026129Heat shock factor protein 1
5d5v_D3e-226816026129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1246254ARLKQKKEQ
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress response. Activated by DREB2A under heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006481891.10.0heat stress transcription factor A-3 isoform X2
SwissprotQ8GYY11e-103HSFA3_ARATH; Heat stress transcription factor A-3
TrEMBLV4S7T00.0V4S7T0_9ROSI; Uncharacterized protein
STRINGXP_006430299.10.0(Citrus clementina)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03720.11e-106heat shock transcription factor A3
Publications ? help Back to Top
  1. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nie S,Yue H,Xing D
    A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.
    Plant Physiol., 2016.
    [PMID:26099269]
  4. Hu Z, et al.
    Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.
    Plant J., 2015. 84(6): p. 1178-91
    [PMID:26576681]
  5. Song C,Chung WS,Lim CO
    Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis.
    Mol. Cells, 2016. 39(6): p. 477-83
    [PMID:27109422]
  6. Kim GD,Cho YH,Lee BH,Yoo SD
    STABILIZED1 Modulates Pre-mRNA Splicing for Thermotolerance.
    Plant Physiol., 2017. 173(4): p. 2370-2382
    [PMID:28223317]
  7. Song C,Lee J,Kim T,Hong JC,Lim CO
    VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis.
    Planta, 2018. 247(6): p. 1439-1448
    [PMID:29536220]