PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla005043

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

C2H2

Protein Properties

Length: 367aa MW: 40636.8 Da PI: 9.5571

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla005043	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.7	2.1e-05	12	34	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C++C+k F r nL+ H r H Cla005043 12 FICEICNKGFQRDQNLQLHRRGH 34 89*******************88 PP
2	zf-C2H2	12.4	0.00048	88	110	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k + +s+ k H + + Cla005043 88 WKCEKCSKKYAVQSDWKAHSKIC 110 58*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.0E-5	11	34	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.94E-7	11	34	No hit	No description
SMART	SM00355	0.022	12	34	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.845	12	34	IPR007087	Zinc finger, C2H2
Pfam	PF12171	4.1E-5	12	34	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	14	34	IPR007087	Zinc finger, C2H2
SMART	SM00355	84	53	83	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.0E-5	76	109	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.94E-7	83	108	No hit	No description
SMART	SM00355	140	88	108	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 367 aa Download sequence Send to blast
MSPKSLMAKN RFICEICNKG FQRDQNLQLH RRGHNLPWKL RQRTSKEVRK KVYVCPEKSC 60 VHHDPARALG DLTGIKKHYS RKHGEKKWKC EKCSKKYAVQ SDWKAHSKIC GTKEYKCDCG 120 TLFSRKDSFI THRAFCDALT EENSRINHHH HHHHHPTFIN NFSPTSSSLL LQPNFVTATV 180 AADQTSLAHN FPNIISDHDG DHKPHPLPLS SPPQLPLWLD PPPNTPNPFF SSATAIHGFS 240 DHPTFFSENH HLFLSEPLTT ASSYAAAPHM SATALLQNAA QMGPTRTPAG PPILFNASTT 300 GAAYGTNNSA AAAAVLSDGR PMKPLMGGAK DEIGGQNFTR DFLGVGNQVV HLTPVGSNQY 360 SDQSRGH

Sequence ? help Back to Top

Protein Sequence Length: 367 aa Download sequence Send to blast

MSPKSLMAKN RFICEICNKG FQRDQNLQLH RRGHNLPWKL RQRTSKEVRK KVYVCPEKSC  60
VHHDPARALG DLTGIKKHYS RKHGEKKWKC EKCSKKYAVQ SDWKAHSKIC GTKEYKCDCG  120
TLFSRKDSFI THRAFCDALT EENSRINHHH HHHHHPTFIN NFSPTSSSLL LQPNFVTATV  180
AADQTSLAHN FPNIISDHDG DHKPHPLPLS SPPQLPLWLD PPPNTPNPFF SSATAIHGFS  240
DHPTFFSENH HLFLSEPLTT ASSYAAAPHM SATALLQNAA QMGPTRTPAG PPILFNASTT  300
GAAYGTNNSA AAAAVLSDGR PMKPLMGGAK DEIGGQNFTR DFLGVGNQVV HLTPVGSNQY  360
SDQSRGH

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-36	84	147	3	66	Zinc finger protein JACKDAW
5b3h_F	1e-36	84	147	3	66	Zinc finger protein JACKDAW
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	38	50	KLRQRTSKEVRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681928	1e-158	LN681928.1 Cucumis melo genomic scaffold, anchoredscaffold00004.
GenBank	LN713266	1e-158	LN713266.1 Cucumis melo genomic chromosome, chr_12.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008463785.1	0.0	PREDICTED: protein indeterminate-domain 2
Swissprot	Q9SCQ6	1e-104	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A1S3CK10	0.0	A0A1S3CK10_CUCME; protein indeterminate-domain 2
STRING	XP_008463785.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	8e-88	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]