PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla009283

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

ERF

Protein Properties

Length: 233aa MW: 26063.5 Da PI: 9.4203

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla009283	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	68.1	1.6e-21	70	119	3	56
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56 y+G+r+++ +g+W+AeIrdp++ r++lg+f taeeAa+a+++a+k+++ge Cla009283 70 YRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAARAYDEAAKRIRGE 119 9*****.******954...4************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	23.894	69	126	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	5.6E-32	69	126	IPR001471	AP2/ERF domain
SMART	SM00380	1.6E-39	69	132	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.57E-22	69	126	IPR016177	DNA-binding domain
CDD	cd00018	2.91E-32	70	125	No hit	No description
Pfam	PF00847	3.1E-15	70	119	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.1E-12	70	81	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.1E-12	92	108	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008219	Biological Process	cell death
GO:0009723	Biological Process	response to ethylene
GO:0009735	Biological Process	response to cytokinin
GO:0009753	Biological Process	response to jasmonic acid
GO:0010286	Biological Process	heat acclimation
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0051707	Biological Process	response to other organism
GO:0005634	Cellular Component	nucleus
GO:0005737	Cellular Component	cytoplasm
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 233 aa Download sequence Send to blast
MCGGAIISDF IERKRTRKLS NESLWSHIDP FSDLLGLNYS PVKSEKPKKR DRATAAVAVE 60 KTPKARKNLY RGIRQRPWGK WAAEIRDPRK GVRVWLGTFN TAEEAARAYD EAAKRIRGEK 120 AKLNFAPAPP SSPPLPAAQP HSPAKKRCVL PELTRGGSNA TGPPPCRRVD NSCDSDEFYY 180 GEELASLRSF LGLDSEEQQA SQFGGNGEFE RVDVDLWMMD DMSLNEQKLS QLV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	1e-21	65	125	10	71	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	11	18	ERKRTRKL

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:9159183}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00109	PBM	Transfer from AT3G16770	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Also induced by cadmium. {ECO:0000269\|PubMed:18836139, ECO:0000269\|PubMed:9159183}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004153075.2	1e-139	PREDICTED: ethylene-responsive transcription factor RAP2-3-like
Swissprot	P42736	4e-50	RAP23_ARATH; Ethylene-responsive transcription factor RAP2-3
TrEMBL	A0A0A0KD18	1e-139	A0A0A0KD18_CUCSA; Uncharacterized protein
STRING	XP_004153075.1	1e-139	(Cucumis sativus)
STRING	XP_004173226.1	1e-139	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4892	33	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G16770.1	5e-42	ethylene-responsive element binding protein

Publications ? help Back to Top
Bueso E, et al. The lithium tolerance of the Arabidopsis cat2 mutant reveals a cross-talk between oxidative stress and ethylene. Plant J., 2007. 52(6): p. 1052-65 [PMID:17931347] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chen YC, et al. Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance. Sci Rep, 2014. 4: p. 5584 [PMID:24998294] Deslauriers SD,Alvarez AA,Lacey RF,Binder BM,Larsen PB Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis. New Phytol., 2015. 208(2): p. 442-55 [PMID:25988998] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Liu W, et al. Ethylene response factor AtERF72 negatively regulates Arabidopsis thaliana response to iron deficiency. Biochem. Biophys. Res. Commun., 2017. 491(3): p. 862-868 [PMID:28390898] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474]