PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla013758

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

C2H2

Protein Properties

Length: 1507aa MW: 169026 Da PI: 6.3911

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla013758	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.5	0.00021	1392	1417	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 ykC C +sF++k +L+ H r+ + Cla013758 1392 YKCDleGCRMSFKTKAELTLHKRNqC 1417 99********************9876 PP
2	zf-C2H2	11.2	0.0012	1475	1501	1	23
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 ykC+ Cg sF+ s++ rH r+ H Cla013758 1475 YKCKveGCGLSFRFVSDYSRHRRKtgH 1501 99*********************9777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00545	2.4E-12	15	55	IPR003349	JmjN domain
PROSITE profile	PS51183	13.661	16	57	IPR003349	JmjN domain
Pfam	PF02375	1.4E-14	17	50	IPR003349	JmjN domain
SMART	SM00558	7.1E-46	276	445	IPR003347	JmjC domain
SuperFamily	SSF51197	1.02E-26	277	443	No hit	No description
PROSITE profile	PS51184	34.87	279	445	IPR003347	JmjC domain
Pfam	PF02373	1.8E-35	309	428	IPR003347	JmjC domain
SMART	SM00355	7.7	1392	1414	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	1.12E-5	1414	1452	No hit	No description
PROSITE profile	PS50157	12.009	1415	1444	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.51	1415	1439	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.8E-4	1416	1443	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	1417	1439	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	6.6E-10	1444	1469	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.946	1445	1474	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0016	1445	1469	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1447	1469	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.56E-10	1455	1497	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.6E-11	1470	1498	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.33	1475	1501	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	1475	1506	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	1477	1501	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009741	Biological Process	response to brassinosteroid
GO:0009826	Biological Process	unidimensional cell growth
GO:0033169	Biological Process	histone H3-K9 demethylation
GO:0048577	Biological Process	negative regulation of short-day photoperiodism, flowering
GO:0048579	Biological Process	negative regulation of long-day photoperiodism, flowering
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 1507 aa Download sequence Send to blast
MGSVEIPKWL KGLPFAPEFR PTDTEFADPI AYISKIEKEA SAFGICKIIP PFPKPSKKYV 60 ISNLNKSLLR STELSRDLNG ANEGEVRAVF TTRHQELGQS VRKAKGVVQN PQFGVHKQVW 120 QSGEVYTLEQ FESKSKVFAR SVLSGIKEPS PLVVESLFWK AASDKPIYVE YANDVPGSAF 180 GEPEGKFRYF HRRRRKRNYY HRSKERSSEP KSEEMQTWTD SPCRDSEGIS NRNDLNTSPE 240 MLKPSTSTVS SEDVSHNSRG KSSDSCTNME GTAGWRLSNS PWNLQVIARS PGSLTRYMPD 300 DIPGVTSPMV YIGMLFSWFA WHVEDHELHS MNFLHVGSPK TWYSIPGDQA FAFEEVVRTQ 360 AYGGNVDHLA ALTLLGEKTT LLSPEIVIAS GIPCCRLIQN PGEFVVTFPR AYHVGFSHGF 420 NCGEAANFGT PQWLSVAKDA AVRRAAMNYL PMLSHQQLLY LLTMSFVSRV PRSLLPGVRS 480 SRLRDRQKEE RELMVKKGFV EDILRENNML SVLLEKESSC RAVLWNPDML SYSSNSQVAN 540 KNSAFPTSPR ENVSCNHIES LDSNVKNMQN FIDEMTLDLE TMNDIYLESD DLSCDFQVDS 600 GTLACVACGI LGFPFMSVVQ PSEKASKELY ADHLSIHKRG GVFGPKDAHC SPHFGGTHPG 660 TKHFHAFLSV YPLELYAHYL LYVTLVKLLI YFAEDSTSVP DVNCLSENLS IASIPKFEKG 720 WNTFSKFLRP RSFCLQHAVE IVELLQKKGG ANVLVICHSD YHKIKANAVA IAEEIGNSFV 780 YNDVQLDIAS EGDLRLIDLA VDEDRDEFRE DWTSRLGINL RHCIKVRKSS PTQQVQHALA 840 LGGLFLTRDH GFNLSALNWL SKRSRSKKIN HLQHCKPFQS MPLKDEVAGE KSDCRIAKSE 900 EKFFQYYRRN KKSGNSIGVS SVTQPASSGD SSDLCNVRSV RSNTSELVIP DSSGMSNQQD 960 AVLQDTSEPN KKAVLPSVDA IDVSFEIHQE QEIIESCNKT NQECDITSEG QSHAGADVCL 1020 DEVNLVDSSG LHSSIRPQSS KLWDNEDVRN LSGEACDGMT SDGDVGEEIE IADTTKDTEE 1080 DSCSSIPIKL QHYSAIQLQF GHLDDRTERE MKPTSRSNES EPNLSNTGTP DVATSNSRDR 1140 TPEVSKVVCE ATNLCNAVTS NNLAHNLQTF EADVEIQSVS GVDVQLKGQQ SSCLADEKSI 1200 ENLGSQEDRD DLSDTLMSST RVEKAPTEPI TPMDEPGPNS CIPGESWPMD VEASGEPWDR 1260 ENLTGEMTQD DDIECADMSR NKHIENPLLS NPSETRDATE ICSSKHKSRS DAVKRRKRKR 1320 DEELIIENEL TSCDFIRSPC EGLRPRVGKN LTNRSGTDVN ITVEDKPERN RVKKRSDSVT 1380 PKLKKEIREG SYKCDLEGCR MSFKTKAELT LHKRNQCPHE GCGKRFSSHK YAMFHQRVHD 1440 DDRPLKCPWK GCSMSFKWAW ARTEHIRVHT GERPYKCKVE GCGLSFRFVS DYSRHRRKTG 1500 HYVDQPA

Sequence ? help Back to Top

Protein Sequence Length: 1507 aa Download sequence Send to blast

MGSVEIPKWL KGLPFAPEFR PTDTEFADPI AYISKIEKEA SAFGICKIIP PFPKPSKKYV  60
ISNLNKSLLR STELSRDLNG ANEGEVRAVF TTRHQELGQS VRKAKGVVQN PQFGVHKQVW  120
QSGEVYTLEQ FESKSKVFAR SVLSGIKEPS PLVVESLFWK AASDKPIYVE YANDVPGSAF  180
GEPEGKFRYF HRRRRKRNYY HRSKERSSEP KSEEMQTWTD SPCRDSEGIS NRNDLNTSPE  240
MLKPSTSTVS SEDVSHNSRG KSSDSCTNME GTAGWRLSNS PWNLQVIARS PGSLTRYMPD  300
DIPGVTSPMV YIGMLFSWFA WHVEDHELHS MNFLHVGSPK TWYSIPGDQA FAFEEVVRTQ  360
AYGGNVDHLA ALTLLGEKTT LLSPEIVIAS GIPCCRLIQN PGEFVVTFPR AYHVGFSHGF  420
NCGEAANFGT PQWLSVAKDA AVRRAAMNYL PMLSHQQLLY LLTMSFVSRV PRSLLPGVRS  480
SRLRDRQKEE RELMVKKGFV EDILRENNML SVLLEKESSC RAVLWNPDML SYSSNSQVAN  540
KNSAFPTSPR ENVSCNHIES LDSNVKNMQN FIDEMTLDLE TMNDIYLESD DLSCDFQVDS  600
GTLACVACGI LGFPFMSVVQ PSEKASKELY ADHLSIHKRG GVFGPKDAHC SPHFGGTHPG  660
TKHFHAFLSV YPLELYAHYL LYVTLVKLLI YFAEDSTSVP DVNCLSENLS IASIPKFEKG  720
WNTFSKFLRP RSFCLQHAVE IVELLQKKGG ANVLVICHSD YHKIKANAVA IAEEIGNSFV  780
YNDVQLDIAS EGDLRLIDLA VDEDRDEFRE DWTSRLGINL RHCIKVRKSS PTQQVQHALA  840
LGGLFLTRDH GFNLSALNWL SKRSRSKKIN HLQHCKPFQS MPLKDEVAGE KSDCRIAKSE  900
EKFFQYYRRN KKSGNSIGVS SVTQPASSGD SSDLCNVRSV RSNTSELVIP DSSGMSNQQD  960
AVLQDTSEPN KKAVLPSVDA IDVSFEIHQE QEIIESCNKT NQECDITSEG QSHAGADVCL  1020
DEVNLVDSSG LHSSIRPQSS KLWDNEDVRN LSGEACDGMT SDGDVGEEIE IADTTKDTEE  1080
DSCSSIPIKL QHYSAIQLQF GHLDDRTERE MKPTSRSNES EPNLSNTGTP DVATSNSRDR  1140
TPEVSKVVCE ATNLCNAVTS NNLAHNLQTF EADVEIQSVS GVDVQLKGQQ SSCLADEKSI  1200
ENLGSQEDRD DLSDTLMSST RVEKAPTEPI TPMDEPGPNS CIPGESWPMD VEASGEPWDR  1260
ENLTGEMTQD DDIECADMSR NKHIENPLLS NPSETRDATE ICSSKHKSRS DAVKRRKRKR  1320
DEELIIENEL TSCDFIRSPC EGLRPRVGKN LTNRSGTDVN ITVEDKPERN RVKKRSDSVT  1380
PKLKKEIREG SYKCDLEGCR MSFKTKAELT LHKRNQCPHE GCGKRFSSHK YAMFHQRVHD  1440
DDRPLKCPWK GCSMSFKWAW ARTEHIRVHT GERPYKCKVE GCGLSFRFVS DYSRHRRKTG  1500
HYVDQPA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6ip0_A	7e-55	8	459	7	346	Transcription factor jumonji (Jmj) family protein
6ip4_A	7e-55	8	459	7	346	Arabidopsis JMJ13
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	1313	1319	KRRKRKR
2	1314	1319	RRKRKR

Functional Description ? help Back to Top
Source	Description
UniProt	Acts probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269\|PubMed:15377760, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19946624}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681821	0.0	LN681821.1 Cucumis melo genomic scaffold, anchoredscaffold00040.
GenBank	LN713257	0.0	LN713257.1 Cucumis melo genomic chromosome, chr_3.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008456505.1	0.0	PREDICTED: probable lysine-specific demethylase ELF6
Swissprot	Q6BDA0	0.0	ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBL	A0A0A0KHH8	0.0	A0A0A0KHH8_CUCSA; Uncharacterized protein
STRING	XP_008456504.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8031	30	34

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G04240.1	0.0	C2H2 family protein

Publications ? help Back to Top
Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A. PLoS ONE, 2013. 8(7): p. e67987 [PMID:23976921] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Crevillén P, et al. Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state. Nature, 2014. 515(7528): p. 587-90 [PMID:25219852] Yang H,Howard M,Dean C Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74 [PMID:27482092]