PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla016368

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

C2H2

Protein Properties

Length: 508aa MW: 56200.1 Da PI: 6.167

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla016368	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21	9.1e-07	260	281	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C +Cgk F+r nL+ H+r H Cla016368 260 FCAICGKGFKRDANLRMHMRGH 281 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.29E-5	257	285	No hit	No description
SMART	SM00355	0.012	259	281	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	11.884	259	286	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	1.2E-5	260	310	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	261	281	IPR007087	Zinc finger, C2H2
SMART	SM00355	59	308	341	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	15	346	368	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 508 aa Download sequence Send to blast
MDPEDSLCSS EVWTKSSFPN NNIQQPAQKW ADASILDYAM EQPFQEFEER TESKASLSCN 60 PNQQIEILDK DSNQMNAALL ASKIQDWDPR AMLNNLSFLE QKIHQLQELV HLIVGRRSQV 120 FGRPDELVVQ QQQLITADLT SIIVQLISTA GSLLPSVKHN LSAAVPAVGQ LEQLDKVLFA 180 SGPGTDNGGV QSQHGDGTKL PELPTQVDGS SKCGKEQNMT VEEHESKDEE DADDNENLPP 240 GSYEILQLEK EEILAPHTHF CAICGKGFKR DANLRMHMRG HGDEYKTAAA LAKPNKEMGS 300 ETMLIKRYSC PFTGCKRNKD HKKFQPLKTI LCVKNHYKRT HCDKSFTCSK CNSKKFSVIA 360 DLKTHEKHCG KDKWLCSCGT TFSRKDKLFG HIALFQGHTP AIPLDESKGA VMSCDRGERY 420 ETMNKLGSIN FSFGSVASGG SSVETIGDAK GGVDDPLSYF SPLNFDSCNF GGFHEFPRPP 480 FENTDNAFSF LIPASSNYTQ KSGAESSS

Sequence ? help Back to Top

Protein Sequence Length: 508 aa Download sequence Send to blast

MDPEDSLCSS EVWTKSSFPN NNIQQPAQKW ADASILDYAM EQPFQEFEER TESKASLSCN  60
PNQQIEILDK DSNQMNAALL ASKIQDWDPR AMLNNLSFLE QKIHQLQELV HLIVGRRSQV  120
FGRPDELVVQ QQQLITADLT SIIVQLISTA GSLLPSVKHN LSAAVPAVGQ LEQLDKVLFA  180
SGPGTDNGGV QSQHGDGTKL PELPTQVDGS SKCGKEQNMT VEEHESKDEE DADDNENLPP  240
GSYEILQLEK EEILAPHTHF CAICGKGFKR DANLRMHMRG HGDEYKTAAA LAKPNKEMGS  300
ETMLIKRYSC PFTGCKRNKD HKKFQPLKTI LCVKNHYKRT HCDKSFTCSK CNSKKFSVIA  360
DLKTHEKHCG KDKWLCSCGT TFSRKDKLFG HIALFQGHTP AIPLDESKGA VMSCDRGERY  420
ETMNKLGSIN FSFGSVASGG SSVETIGDAK GGVDDPLSYF SPLNFDSCNF GGFHEFPRPP  480
FENTDNAFSF LIPASSNYTQ KSGAESSS

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681794	0.0	LN681794.1 Cucumis melo genomic scaffold, anchoredscaffold00061.
GenBank	LN713255	0.0	LN713255.1 Cucumis melo genomic chromosome, chr_1.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008461471.1	0.0	PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A1S3CEP8	0.0	A0A1S3CEP8_CUCME; protein SENSITIVE TO PROTON RHIZOTOXICITY 1
STRING	XP_008461471.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5340	32	54

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	0.0	C2H2 family protein

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]