PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla021661

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

bHLH

Protein Properties

Length: 150aa MW: 16458.9 Da PI: 9.8699

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla021661	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	12.2	0.00033	2	18	4	20
HHHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsaf 20 ah ++Er+RR+++N+ + Cla021661 2 AHIAVERNRRRQMNEHL 18 8*************976 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.62E-8	1	50	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.46E-5	1	41	No hit	No description
PROSITE profile	PS51671	8.711	104	150	IPR002912	ACT domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008152	Biological Process	metabolic process
GO:0009913	Biological Process	epidermal cell differentiation
GO:0010374	Biological Process	stomatal complex development
GO:0005634	Cellular Component	nucleus
GO:0016597	Molecular Function	amino acid binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 150 aa Download sequence Send to blast
MAHIAVERNR RRQMNEHLRG DQASIIGGVI EFIKELHQVL QSLESNKRRR KSISPSPGPS 60 PRPQSMAGSN NGSLGFENGV DVVGACCNSS VADVEAKISG SNVVLKIISR RIPGQLSKMI 120 GVFERLSFEV LHLNISSMDD TVLYSFVVKE

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata. {ECO:0000269\|PubMed:17183265, ECO:0000269\|PubMed:17183267}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV, flagellin, and jasmonic acid (JA) treatments. {ECO:0000269\|PubMed:12679534}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681848	1e-122	LN681848.1 Cucumis melo genomic scaffold, anchoredscaffold00006.
GenBank	LN713260	1e-122	LN713260.1 Cucumis melo genomic chromosome, chr_6.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011650991.1	9e-80	PREDICTED: transcription factor MUTE
Swissprot	Q9M8K6	2e-55	MUTE_ARATH; Transcription factor MUTE
TrEMBL	A0A0A0L8U9	2e-78	A0A0A0L8U9_CUCSA; Uncharacterized protein
STRING	XP_004134456.1	4e-79	(Cucumis sativus)
STRING	XP_004172922.1	4e-79	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF11252	30	36

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G06120.1	2e-53	bHLH family protein

Publications ? help Back to Top
Casson S,Gray JE Influence of environmental factors on stomatal development. New Phytol., 2008. 178(1): p. 9-23 [PMID:18266617] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Balcerowicz M,Ranjan A,Rupprecht L,Fiene G,Hoecker U Auxin represses stomatal development in dark-grown seedlings via Aux/IAA proteins. Development, 2014. 141(16): p. 3165-76 [PMID:25063454] de Marcos A, et al. Transcriptional profiles of Arabidopsis stomataless mutants reveal developmental and physiological features of life in the absence of stomata. Front Plant Sci, 2015. 6: p. 456 [PMID:26157447] Mahoney AK, et al. Functional analysis of the Arabidopsis thaliana MUTE promoter reveals a regulatory region sufficient for stomatal-lineage expression. Planta, 2016. 243(4): p. 987-98 [PMID:26748914] Klermund C, et al. LLM-Domain B-GATA Transcription Factors Promote Stomatal Development Downstream of Light Signaling Pathways in Arabidopsis thaliana Hypocotyls. Plant Cell, 2016. 28(3): p. 646-60 [PMID:26917680] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] Qi X, et al. Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling. Elife, 2018. [PMID:28266915] Raissig MT, et al. Mobile MUTE specifies subsidiary cells to build physiologically improved grass stomata. Science, 2017. 355(6330): p. 1215-1218 [PMID:28302860] Lee JH,Jung JH,Park CM Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis. Plant Cell, 2017. 29(11): p. 2817-2830 [PMID:29070509] Han SK, et al. MUTE Directly Orchestrates Cell-State Switch and the Single Symmetric Division to Create Stomata. Dev. Cell, 2018. 45(3): p. 303-315.e5 [PMID:29738710]