PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_24012_BGI-A2_v1.0
Organism
Gossypium arboreum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family WRKY
Protein Properties Length: 472aa    MW: 51005.9 Da    PI: 5.2864
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_24012_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY96.42e-30247305259
                                 --SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
                        WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                                  Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+aed +++++tYeg+Hnh+
  Cotton_A_24012_BGI-A2_v1.0 247 TDGCQWRKYGQKMAKGNPCPRAYYRCTMAtGCPVRKQVQRCAEDRTILITTYEGNHNHT 305
                                 7***************************99****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.802.0E-33231307IPR003657WRKY domain
SuperFamilySSF1182901.96E-27239307IPR003657WRKY domain
PROSITE profilePS5081129.172241307IPR003657WRKY domain
SMARTSM007745.4E-36246306IPR003657WRKY domain
PfamPF031062.8E-26248304IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 472 aa     Download sequence    Send to blast
MAKTSGLSID FDPNYFLIHN PPVLNSFPEY TPKDTNKNNN NNNTMFSGTT TTPENMSLPS  60
TVDRFPVKFD CFYDQTRPSF LPSDDDKRRV VGELDFFAEK NDKLVDDADF MHTSDAGLEL  120
NVNIGLNLLT TNTSADQSTM EDKKANNEVA VLRAKLVQMN AENERLKEML IQATENYNTM  180
KIHLYLGLAV AAEADESSPS SPEGKSQRED SSGGDNKVPR LDVDQSEAAM RKARVSVRAR  240
SEAPMITDGC QWRKYGQKMA KGNPCPRAYY RCTMATGCPV RKQVQRCAED RTILITTYEG  300
NHNHTLPPSA MSMASTTSSA ARMLVSGSTS SPDGLMNSNL LTTTLLPCSS TMATVSASTP  360
FPSVTLDLTQ SSFSTPPPPY NVANSVAVTA PLVPQVSGQA HDNLSKFAGI QMSKDLDRLQ  420
QGEQNSIGDT VNAATGAIAT DPSFAAALAA AITSIIASSQ SHPNNGHNSN AM
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A7e-23233308175WRKY transcription factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269|PubMed:12000796, ECO:0000269|PubMed:25733771}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF0310950.0KF031095.1 Gossypium hirsutum WRKY transcription factor 54 (WRKY54) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016725646.10.0PREDICTED: probable WRKY transcription factor 31
SwissprotQ9C5191e-107WRKY6_ARATH; WRKY transcription factor 6
TrEMBLA0A059Q7A60.0A0A059Q7A6_GOSHI; WRKY transcription factor 54
STRINGGorai.001G094300.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM2479434
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G62300.19e-83WRKY family protein
Publications ? help Back to Top
  1. Zhou F, et al.
    High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression.
    Plant J., 2004. 39(6): p. 920-32
    [PMID:15341634]
  2. Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P
    An extracellular subtilase switch for immune priming in Arabidopsis.
    PLoS Pathog., 2013. 9(6): p. e1003445
    [PMID:23818851]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Singh V,Roy S,Singh D,Nandi AK
    Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes.
    J. Biosci., 2014. 39(1): p. 119-26
    [PMID:24499796]
  5. Ali MA,Wieczorek K,Kreil DP,Bohlmann H
    The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots.
    PLoS ONE, 2014. 9(7): p. e102360
    [PMID:25033038]
  6. Chai J,Liu J,Zhou J,Xing D
    Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid.
    J. Exp. Bot., 2014. 65(22): p. 6513-28
    [PMID:25210078]
  7. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  8. Xiao D, et al.
    SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis.
    Plant Physiol., 2015. 169(2): p. 1275-91
    [PMID:26304848]
  9. Bakshi M, et al.
    WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis.
    BMC Plant Biol., 2015. 15: p. 305
    [PMID:26718529]
  10. Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF
    Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development.
    PLoS Genet., 2016. 12(2): p. e1005833
    [PMID:26829043]
  11. Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P
    Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis.
    PLoS Pathog., 2016. 12(11): p. e1006003
    [PMID:27806116]
  12. Li H, et al.
    BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis.
    Mol Plant, 2017. 10(4): p. 545-559
    [PMID:28089951]
  13. Stetter MG,Benz M,Ludewig U
    Increased root hair density by loss of WRKY6 in Arabidopsis thaliana.
    PeerJ, 2017. 5: p. e2891
    [PMID:28149680]
  14. Zhou X, et al.
    StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato.
    J. Exp. Bot., 2017. 68(5): p. 1265-1281
    [PMID:28338870]
  15. Bakshi M, et al.
    Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation.
    Front Microbiol, 2017. 8: p. 1262
    [PMID:28747898]
  16. Zhang Y, et al.
    DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6.
    Plant Cell Rep., 2018. 37(7): p. 981-992
    [PMID:29574486]