PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_29266_BGI-A2_v1.0
Common NameF383_19088
Organism
Gossypium arboreum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family E2F/DP
Protein Properties Length: 366aa    MW: 41715.1 Da    PI: 9.5188
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_29266_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP74.51.1e-231984171
                     E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                                rkeksL+ll+++fl+l+++ + +++ l+++a++L    v  +rRRiYD++N+Le+++++++k kn++ wkg
  Cotton_A_29266_BGI-A2_v1.0 19 RKEKSLGLLCSNFLALYNHDSVQTIGLDDAASKL---GV--ERRRIYDVVNILESIGVVARKGKNQYLWKG 84
                                79*****************999************...**..****************************98 PP
2E2F_TDP75.65e-24146225271
                     E2F_TDP   2 keksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                                 +eksL+l+tq+f+kl+ +s+++ +tl+++a +L+ +      v++k+RR+YDi+NV++++nliek     ++k+++rw g
  Cotton_A_29266_BGI-A2_v1.0 146 REKSLWLITQNFVKLFLCSDAELITLDSAAIALLGDvhnstAVRTKVRRLYDIANVFSSMNLIEKthhpeSRKPAFRWLG 225
                                 79***************************************************************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.7E-251785IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.15E-161982IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-291984IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.1E-202084IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.0E-21140226IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.6E-29145225IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.1E-17147225IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.42E-12147226IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 366 aa     Download sequence    Send to blast
MSSFASQESE SNSRTLYCRK EKSLGLLCSN FLALYNHDSV QTIGLDDAAS KLGVERRRIY  60
DVVNILESIG VVARKGKNQY LWKGFGEIPK ALEKLKEEAL KQNFCFSDCS KSLRVLDENE  120
SADSSYVKNE GQDNLSESSK RTDTKREKSL WLITQNFVKL FLCSDAELIT LDSAAIALLG  180
DVHNSTAVRT KVRRLYDIAN VFSSMNLIEK THHPESRKPA FRWLGWRAKL HNGSTTALEL  240
NESKKRTFGT EITNQNLKRT KANSSAHRRL NQKENTGMHI KLDSVEHDHK MQQHSKQCSK  300
GFAFGPFTPA AISSGNRNVR PIRDWESLAS IYKPQYLNQA LSDLFAHYME AWNSWYAEVA  360
RKEEIH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-36192194232Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017610792.10.0PREDICTED: E2F transcription factor-like E2FF isoform X1
SwissprotQ8RWL01e-121E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A0B0MCL90.0A0A0B0MCL9_GOSAR; E2F transcription factor-like E2FF
STRINGGorai.006G027400.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-115DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]