PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cotton_A_31963_BGI-A2_v1.0

Common Name

F383_26117

Organism

Gossypium arboreum

Taxonomic ID

29729

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

C2H2

Protein Properties

Length: 1516aa MW: 168926 Da PI: 6.853

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_31963_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.8	0.00076	1403	1426	3	23
ET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 3 Cp..dCgksFsrksnLkrHirt.H 23 C C++sF++k++L+ H r+ + Cotton_A_31963_BGI-A2_v1.0 1403 CDleGCHMSFKTKEELRLHKRNrC 1426 77779***************9877 PP
2	zf-C2H2	11.1	0.0013	1425	1448	2	23
EET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirtH 23 +Cp Cgk F+++ + + H+r+H Cotton_A_31963_BGI-A2_v1.0 1425 RCPyeGCGKKFRSHKYAVLHQRVH 1448 69999*****************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00545	8.5E-14	15	55	IPR003349	JmjN domain
PROSITE profile	PS51183	13.883	16	57	IPR003349	JmjN domain
Pfam	PF02375	9.1E-15	17	50	IPR003349	JmjN domain
SuperFamily	SSF51197	9.61E-12	280	364	No hit	No description
SMART	SM00558	1.4E-13	284	472	IPR003347	JmjC domain
PROSITE profile	PS51184	20.892	284	472	IPR003347	JmjC domain
Pfam	PF02373	9.2E-18	317	404	IPR003347	JmjC domain
SMART	SM00355	22	1401	1423	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	0.036	1424	1448	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	11.863	1424	1453	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.43E-5	1424	1461	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-4	1425	1452	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	1426	1448	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	6.6E-10	1453	1478	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.946	1454	1483	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0016	1454	1478	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1456	1478	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.16E-9	1464	1506	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.8E-10	1479	1507	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.66	1484	1510	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.767	1484	1515	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	1486	1510	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009741	Biological Process	response to brassinosteroid
GO:0009826	Biological Process	unidimensional cell growth
GO:0032259	Biological Process	methylation
GO:0033169	Biological Process	histone H3-K9 demethylation
GO:0048577	Biological Process	negative regulation of short-day photoperiodism, flowering
GO:0048579	Biological Process	negative regulation of long-day photoperiodism, flowering
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0008168	Molecular Function	methyltransferase activity
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 1516 aa Download sequence Send to blast
MGNVEIPKWL KRLPLAPEFR PTDTEFADPI AYISKIEKEA GAYGICKIIP PLPKPSKKYV 60 FNNLNRSLSK SPELGSDVNI GSVSNFGDSG GDERERRAVF TTRHQELGWS GKRMKGVVSS 120 PQCGAQKQVW QSGEIYTLEQ FESKSKTFAK SLLGLLKEVS PLHIEALFWK VASEKSIYVE 180 YANDVPGSGF GEPEGQFRYF HRRRRKRMSY RRENSDCRKD EIDAVNYSQM VEINNTSVKS 240 DPDTRVETPK SSTTLSTIAS DVNSHSKRKS GNASNDMEGT AGWKLSNSPW NLQVIARSAG 300 SLTRFMPDDI PGVTSPMVYI GMLFSWFAWH VEDHELHSMN FLHTGSSKTW YAVPGDHAFA 360 FEEVIRAEAY GGNIDRLAAL SLLGEKTTLL SPELIVASGI PCCRRSLSYH DQAVDDGDLI 420 NEYVKKVFKM SSEVGLLTCK DPYNVCFNCG EAANFGTPQW LQVAKEAAVR RAAMNYLPML 480 SHQQLLYLLT MSFMSRVPRS LLPGARSSRL RDRLKEEREV LVKKAFVEDL LTENKLLSLL 540 LKKGSTYRAI MWDPLLLPYT SRDSELPSRT ATDSTIMQEN VSDINGEDKS DQKNLLDEMC 600 FYMENLNYLY SNDDDLTCDF QVDSGTLVCV ACGILGYPFM SVVQPSKGAA VEFLPVDHLS 660 SQGSTVLVPK NAHSCPVEGS VSDNLNHVPD LSLPFKHSAL PSITKFSDGW DTSNKYLRPR 720 IFCLEHAVQV EELLRSKGGA KMLIICHSDY QKIKANAIPV ADDIGIPFNY NDVPLDAASE 780 EDLNLINFTI DDEHDEIQED WTSKLGVNLR YCVKVRKNSS FKQVQHALPL SGLFTDKYSS 840 LELFNIKWKS RKSRSKGKLN HPSPSKPCES VEMKVDEIMV EKLDSDISKY GQKIIQYSRR 900 KKRKSDYSTG GGGGVELLKN DLPREDSAAS SQLLDKHGGN KSKINARSES IQAQLEVPTT 960 SVVQRDQNKI VEESGPDDEA QSLIACASSI KKCENKLMER NSENDESSPA EKCSKFCLVA 1020 DDEVYLENTA TATKVCNPVS EQQSDEPTSG YGLINGNSAS SHSAQRCAGR YNQGLEDITV 1080 PKFSINGGAF SGMTSENEVQ QGTEATSRNN SEVIIRSEVL KEPFAAADSC DGTVSQNKAQ 1140 KQEIRINARK EVLSGSFTSA GIDHQSTDLS VEEYSTISKN PGAEEDCHTD VTLDVEVFQE 1200 IQATKGTGGD EVITCSDLPM QEKQPTPVMM EACSEIQQDS SSSKKPCVGA TADADSHEND 1260 PNRYEKNEES ASCCRTPINQ TTIPIQKYSR AHRDTYATVN VNDGTGVCSS VENGDLESAM 1320 VNCKSNAMGR KRKRELEETC QKVGSDGFIR SPCEGLRPRA RKDATSSFDA DKASSEGLQT 1380 KETRKPSTHA HRKIIIKKGS HGCDLEGCHM SFKTKEELRL HKRNRCPYEG CGKKFRSHKY 1440 AVLHQRVHDD DRPLKCPWKG CSMSFKWAWA RTEHIRVHTG ERPYKCKVEG CSLSFRFVSD 1500 FSRHRRKTGH YIDSSA

Sequence ? help Back to Top

Protein Sequence Length: 1516 aa Download sequence Send to blast

MGNVEIPKWL KRLPLAPEFR PTDTEFADPI AYISKIEKEA GAYGICKIIP PLPKPSKKYV  60
FNNLNRSLSK SPELGSDVNI GSVSNFGDSG GDERERRAVF TTRHQELGWS GKRMKGVVSS  120
PQCGAQKQVW QSGEIYTLEQ FESKSKTFAK SLLGLLKEVS PLHIEALFWK VASEKSIYVE  180
YANDVPGSGF GEPEGQFRYF HRRRRKRMSY RRENSDCRKD EIDAVNYSQM VEINNTSVKS  240
DPDTRVETPK SSTTLSTIAS DVNSHSKRKS GNASNDMEGT AGWKLSNSPW NLQVIARSAG  300
SLTRFMPDDI PGVTSPMVYI GMLFSWFAWH VEDHELHSMN FLHTGSSKTW YAVPGDHAFA  360
FEEVIRAEAY GGNIDRLAAL SLLGEKTTLL SPELIVASGI PCCRRSLSYH DQAVDDGDLI  420
NEYVKKVFKM SSEVGLLTCK DPYNVCFNCG EAANFGTPQW LQVAKEAAVR RAAMNYLPML  480
SHQQLLYLLT MSFMSRVPRS LLPGARSSRL RDRLKEEREV LVKKAFVEDL LTENKLLSLL  540
LKKGSTYRAI MWDPLLLPYT SRDSELPSRT ATDSTIMQEN VSDINGEDKS DQKNLLDEMC  600
FYMENLNYLY SNDDDLTCDF QVDSGTLVCV ACGILGYPFM SVVQPSKGAA VEFLPVDHLS  660
SQGSTVLVPK NAHSCPVEGS VSDNLNHVPD LSLPFKHSAL PSITKFSDGW DTSNKYLRPR  720
IFCLEHAVQV EELLRSKGGA KMLIICHSDY QKIKANAIPV ADDIGIPFNY NDVPLDAASE  780
EDLNLINFTI DDEHDEIQED WTSKLGVNLR YCVKVRKNSS FKQVQHALPL SGLFTDKYSS  840
LELFNIKWKS RKSRSKGKLN HPSPSKPCES VEMKVDEIMV EKLDSDISKY GQKIIQYSRR  900
KKRKSDYSTG GGGGVELLKN DLPREDSAAS SQLLDKHGGN KSKINARSES IQAQLEVPTT  960
SVVQRDQNKI VEESGPDDEA QSLIACASSI KKCENKLMER NSENDESSPA EKCSKFCLVA  1020
DDEVYLENTA TATKVCNPVS EQQSDEPTSG YGLINGNSAS SHSAQRCAGR YNQGLEDITV  1080
PKFSINGGAF SGMTSENEVQ QGTEATSRNN SEVIIRSEVL KEPFAAADSC DGTVSQNKAQ  1140
KQEIRINARK EVLSGSFTSA GIDHQSTDLS VEEYSTISKN PGAEEDCHTD VTLDVEVFQE  1200
IQATKGTGGD EVITCSDLPM QEKQPTPVMM EACSEIQQDS SSSKKPCVGA TADADSHEND  1260
PNRYEKNEES ASCCRTPINQ TTIPIQKYSR AHRDTYATVN VNDGTGVCSS VENGDLESAM  1320
VNCKSNAMGR KRKRELEETC QKVGSDGFIR SPCEGLRPRA RKDATSSFDA DKASSEGLQT  1380
KETRKPSTHA HRKIIIKKGS HGCDLEGCHM SFKTKEELRL HKRNRCPYEG CGKKFRSHKY  1440
AVLHQRVHDD DRPLKCPWKG CSMSFKWAWA RTEHIRVHTG ERPYKCKVEG CSLSFRFVSD  1500
FSRHRRKTGH YIDSSA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6a57_A	1e-51	1399	1515	21	137	Lysine-specific demethylase REF6
6a58_A	1e-51	1399	1515	21	137	Lysine-specific demethylase REF6
6a59_A	1e-51	1399	1515	21	137	Lysine-specific demethylase REF6
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269\|PubMed:15377760, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19946624}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017606763.1	0.0	PREDICTED: probable lysine-specific demethylase ELF6
Swissprot	Q6BDA0	0.0	ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBL	A0A0B0MQH6	0.0	A0A0B0MQH6_GOSAR; Putative lysine-specific demethylase ELF6-like protein
STRING	Gorai.009G313100.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM11520	27	31

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G04240.1	0.0	C2H2 family protein

Publications ? help Back to Top
Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A. PLoS ONE, 2013. 8(7): p. e67987 [PMID:23976921] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Crevillén P, et al. Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state. Nature, 2014. 515(7528): p. 587-90 [PMID:25219852] Yang H,Howard M,Dean C Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74 [PMID:27482092]