PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_40148_BGI-A2_v1.0
Organism
Gossypium arboreum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family MIKC_MADS
Protein Properties Length: 260aa    MW: 29794.1 Da    PI: 10.0892
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_40148_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF99.21.7e-31958150
                                S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE CS
                      SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeys 50
                                krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i+fss+g+lyey+
  Cotton_A_40148_BGI-A2_v1.0  9 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYA 58
                                79***********************************************8 PP
2K-box114.51e-37761724100
                       K-box   4 ssgksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkeke 86 
                                 s++ s++e +a+ +qqe++kL+++i+nLq+ +Rh+lGe+++ L +keL++Le++Lek++++iRskKnell+++ie++qk+e +
  Cotton_A_40148_BGI-A2_v1.0  76 SNTGSVAEVNAQFYQQEADKLRNQIRNLQNANRHMLGESIGGLPMKELKSLESRLEKGISRIRSKKNELLFAEIEYMQKREID 158
                                 3344499**************************************************************************** PP

                       K-box  87 lqeenkaLrkklee 100
                                 l+++n+ Lr+k++e
  Cotton_A_40148_BGI-A2_v1.0 159 LHNNNQLLRAKIAE 172
                                 ***********986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006634.132161IPR002100Transcription factor, MADS-box
SMARTSM004321.1E-42160IPR002100Transcription factor, MADS-box
SuperFamilySSF554554.45E-34290IPR002100Transcription factor, MADS-box
CDDcd002652.32E-46276No hitNo description
PRINTSPR004045.1E-33323IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PfamPF003191.0E-261057IPR002100Transcription factor, MADS-box
PRINTSPR004045.1E-332338IPR002100Transcription factor, MADS-box
PRINTSPR004045.1E-333859IPR002100Transcription factor, MADS-box
PfamPF014861.1E-2785170IPR002487Transcription factor, K-box
PROSITE profilePS5129714.99986176IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0048366Biological Processleaf development
GO:0048440Biological Processcarpel development
GO:0048443Biological Processstamen development
GO:0048497Biological Processmaintenance of floral organ identity
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 260 aa     Download sequence    Send to blast
MGRGKIEIKR IENTTNRQVT FCKRRNGLLK KAYELSVLCD AEVALIVFSS RGRLYEYANN  60
SVKATIERYK KASDSSNTGS VAEVNAQFYQ QEADKLRNQI RNLQNANRHM LGESIGGLPM  120
KELKSLESRL EKGISRIRSK KNELLFAEIE YMQKREIDLH NNNQLLRAKI AENERKQQSM  180
NLMPGGSSAN FEALHSQPYD SRNYFQVDAL QPATNYYNPQ QQQDQIALQL LMLWGRAWFI  240
AAVSVLVKNI LALCQMKATI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tqe_P2e-21184184Myocyte-specific enhancer factor 2B
1tqe_Q2e-21184184Myocyte-specific enhancer factor 2B
1tqe_R2e-21184184Myocyte-specific enhancer factor 2B
1tqe_S2e-21184184Myocyte-specific enhancer factor 2B
6c9l_A2e-21184184Myocyte-specific enhancer factor 2B
6c9l_B2e-21184184Myocyte-specific enhancer factor 2B
6c9l_C2e-21184184Myocyte-specific enhancer factor 2B
6c9l_D2e-21184184Myocyte-specific enhancer factor 2B
6c9l_E2e-21184184Myocyte-specific enhancer factor 2B
6c9l_F2e-21184184Myocyte-specific enhancer factor 2B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the control of organ identity during the early development of flowers. Is required for normal development of stamens and carpels in the wild-type flower. Plays a role in maintaining the determinacy of the floral meristem. Acts as C class cadastral protein by repressing the A class floral homeotic genes like APETALA1. Forms a heterodimer via the K-box domain with either SEPALATTA1/AGL2, SEPALATTA2/AGL4, SEPALLATA3/AGL9 or AGL6 that could be involved in genes regulation during floral meristem development. Controls AHL21/GIK, a multifunctional chromatin modifier in reproductive organ patterning and differentiation (PubMed:19956801). Induces microsporogenesis through the activation of SPL/NZZ (PubMed:15254538). {ECO:0000269|PubMed:15254538, ECO:0000269|PubMed:19956801}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00609ChIP-seqTransfer from AT4G18960Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Negatively regulated by the A class floral homeotic protein APETALA2 and by other repressors like LEUNIG, SEUSS, SAP or CURLY LEAF. Positively regulated by both LEAFY and APETALA1. Repressed by silencing mediated by polycomb group (PcG) protein complex containing EMF1 and EMF2. Up-regulated by HUA2. {ECO:0000269|PubMed:10198637, ECO:0000269|PubMed:11058164, ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:17794879, ECO:0000269|PubMed:18281509, ECO:0000269|PubMed:19783648, ECO:0000269|PubMed:9783581}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEU8815100.0EU881510.1 Gossypium hirsutum MADS10 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012466276.11e-169PREDICTED: floral homeotic protein AGAMOUS-like isoform X3
RefseqXP_012466277.11e-169PREDICTED: floral homeotic protein AGAMOUS-like isoform X3
RefseqXP_017647128.11e-169PREDICTED: floral homeotic protein AGAMOUS-like isoform X1
RefseqXP_017647129.11e-169PREDICTED: floral homeotic protein AGAMOUS-like isoform X1
RefseqXP_017647131.11e-169PREDICTED: floral homeotic protein AGAMOUS-like isoform X2
SwissprotP178391e-123AG_ARATH; Floral homeotic protein AGAMOUS
TrEMBLA0A0D2WAI11e-168A0A0D2WAI1_GOSRA; Uncharacterized protein
STRINGGorai.N017200.11e-167(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM61812237
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G18960.11e-121MIKC_MADS family protein
Publications ? help Back to Top
  1. Huang Z, et al.
    APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana.
    New Phytol., 2017. 215(3): p. 1197-1209
    [PMID:27604611]
  2. Rong XF, et al.
    Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis.
    Plant Cell Physiol., 2018. 59(4): p. 756-764
    [PMID:29186581]
  3. Uemura A, et al.
    Regulation of floral meristem activity through the interaction of AGAMOUS, SUPERMAN, and CLAVATA3 in Arabidopsis.
    Plant Reprod, 2018. 31(1): p. 89-105
    [PMID:29218596]