PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa01g001130.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 351aa    MW: 39720.7 Da    PI: 8.7717
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa01g001130.1genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP71.21.2e-221681171
         E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                    rkeksL+ll ++fl+l+++ +++ + l+++a +L    v  +rRRiYD++N+Le+++++++k kn ++w+g
  Csa01g001130.1 16 RKEKSLGLLVSNFLRLYNRDDADLIGLDDAAGKL---GV--ERRRIYDVVNILESIGIVARKGKNMYSWRG 81
                    79********************************...**..****************************98 PP

2E2F_TDP85.73.4e-27141221171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     rkeksL+ll+q+f+k++ +s+++ +tl+++ak+L+s+     ++++k+RR+YDi+NV++++nliek     ++k+++rw g
  Csa01g001130.1 141 RKEKSLWLLSQNFVKMFLCSDDDLITLDSAAKALLSDsqdpvHMRTKVRRLYDIANVFSSMNLIEKtqipeTKKPAYRWLG 221
                     79********************************************************************99*******87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.1E-241382IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.07E-151579IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.5E-261681IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.7E-181781IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.1E-22138223IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.9E-32141221IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.0E-20142221IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.67E-13143222IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 351 aa     Download sequence    Send to blast
MVSQDAESLA LQTYSRKEKS LGLLVSNFLR LYNRDDADLI GLDDAAGKLG VERRRIYDVV  60
NILESIGIVA RKGKNMYSWR GFGEIPRSLD KLKEEGMREK LCISSTNNSD KVSDDVEREE  120
SSFSLTPDDQ ETSSSSKIDQ RKEKSLWLLS QNFVKMFLCS DDDLITLDSA AKALLSDSQD  180
PVHMRTKVRR LYDIANVFSS MNLIEKTQIP ETKKPAYRWL GSESIAETGT SLFNSDEPKK  240
RVFGTEITNL RAKRNKTDCS SNGKQIGYKK HDDANTEQES KPAASKYVFG PSFPTGAASK  300
KNENVRKGRL QEIESLASTY KPQYCNKEIT SLLGHFTETW KRWYAELDRK *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-34152133228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa01g001130.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010501826.10.0PREDICTED: E2F transcription factor-like E2FF
RefseqXP_019099212.10.0PREDICTED: E2F transcription factor-like E2FF
SwissprotQ8RWL00.0E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLR0HMF00.0R0HMF0_9BRAS; Uncharacterized protein
STRINGXP_010501826.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.10.0DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]