PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa04g031200.1
Organism
Camelina sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 410aa    MW: 46317.8 Da    PI: 7.4348
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa04g031200.1genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.35.3e-2336101171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     rk+ksL+ll+++fl+l+++   +++ l+++a +L    v  +rRRiYDi+NVLe+++++++++kn+++wkg
  Csa04g031200.1  36 RKQKSLGLLCTNFLALYNRDGIDTIGLDDAAFKL---GV--ERRRIYDIVNVLESVGVLTRRAKNQYTWKG 101
                     79*****************999************...**..****************************98 PP
2E2F_TDP79.92.2e-25177257171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     r+eksL+lltq+f+kl+ +se++i++l+e+ak L+ +      +++k+RR+YDi+NVL+++nliek     ++k++++w g
  Csa04g031200.1 177 RREKSLGLLTQNFIKLFICSEARIISLDEAAKLLLGDahntsIMRTKVRRLYDIANVLSSMNLIEKthtldSRKPAFKWLG 257
                     689**************************************999************************9999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.4E-2532102IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.46E-163599IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.4E-2736101IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.2E-2037101IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.1E-23175258IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.7E-32177257IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467855.9E-14179258IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023195.4E-20179257IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 410 aa     Download sequence    Send to blast
MSDLPPERSI VPITSSSPVY MPESSSYLQL HHSYSRKQKS LGLLCTNFLA LYNRDGIDTI  60
GLDDAAFKLG VERRRIYDIV NVLESVGVLT RRAKNQYTWK GFAAIPAALK ELQEVFLMQE  120
EAVKDTFHRF YVNENVKGSD DEDDDEESSQ PHSSSQTDSS KPGSLPQSSD SPKLDNRREK  180
SLGLLTQNFI KLFICSEARI ISLDEAAKLL LGDAHNTSIM RTKVRRLYDI ANVLSSMNLI  240
EKTHTLDSRK PAFKWLGYNG EPTFTLSSDL LQMESRKRAF GTDLTNVNVK RSKSSSSSQD  300
NATERRLKMK KHSTAESSYN KSFDVYESRH GSTGYQFGPF APGTGTYPTA VLEDNSRRAF  360
DVENLVSDHH PSYQNQVLKD LFSHYMDAWN TWYSEVIQKN PLPNASQHR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A8e-38352493228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa04g031200.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0745330.0AB074533.1 Arabidopsis thaliana mRNA for E2F-like repressor E2L3, complete cds.
GenBankBT0042580.0BT004258.1 Arabidopsis thaliana clone RAFL15-19-A14 (R20743) putative DP-E2F protein 1 (At3g48160) mRNA, complete cds.
GenBankBT0055240.0BT005524.1 Arabidopsis thaliana clone U20743 putative DP-E2F protein 1 (At3g48160) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010503439.10.0PREDICTED: E2F transcription factor-like E2FE
SwissprotQ8LSZ40.0E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLD7LRJ40.0D7LRJ4_ARALL; Uncharacterized protein
STRINGXP_010503439.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM63042743
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.20.0DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]