PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Csa19g003230.1

Organism

Camelina sativa

Taxonomic ID

90675

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

E2F/DP

Protein Properties

Length: 415aa MW: 46232.5 Da PI: 8.4331

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa19g003230.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	85.3	4.6e-27	128	208	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 rkeksL+ll+q+f+k++ +s+++ +tl+++ak+L+s+ ++++k+RR+YDi+NV++++nliek ++k+++rw g Csa19g003230.1 128 RKEKSLWLLSQNFVKMFLCSDDDLITLDSAAKALLSDsqdpvHMRTKVRRLYDIANVFSSMNLIEKtqipeTKKPAYRWLG 208 79******************************************************************99*****87 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	2.8E-22	125	210	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	3.9E-32	128	208	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.2E-19	129	208	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	9.79E-13	130	209	IPR011991	Winged helix-turn-helix DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 415 aa Download sequence Send to blast
MSSYAMVSQD AESLALQTYS RKEKSLGLLV SKLIELSSFH PLADSSLWSY ILTQIVARKG 60 KNMYSWKGFK EVPRSLDKLK EEGMREKLCI SSTNNSDKVS DDVQREESSF SLTPDDQETS 120 SSSKIDQRKE KSLWLLSQNF VKMFLCSDDD LITLDSAAKA LLSDSQDPVH MRTKVRRLYD 180 IANVFSSMNL IEKTQIPETK KPAYRWLGSE SIAETGTSLF NSDEPKKRVF GTEITNLRAK 240 RNKTDCSSNG KQIGYKKHDD ANTEQESKPA ASKYVFGPSF PTGASKKNEY VRKGRLQEIE 300 SLASTYKPQY CNKGSKLNVA FLVFLAMLSA VLGGVAQESW TALFGTLYYF ISAISLVNSH 360 CLAADHSEFL NNNGENANAN AVSNPFFQFP LLPVSLPHVH SCYSCISLLL SLIL*

Sequence ? help Back to Top

Protein Sequence Length: 415 aa Download sequence Send to blast

MSSYAMVSQD AESLALQTYS RKEKSLGLLV SKLIELSSFH PLADSSLWSY ILTQIVARKG  60
KNMYSWKGFK EVPRSLDKLK EEGMREKLCI SSTNNSDKVS DDVQREESSF SLTPDDQETS  120
SSSKIDQRKE KSLWLLSQNF VKMFLCSDDD LITLDSAAKA LLSDSQDPVH MRTKVRRLYD  180
IANVFSSMNL IEKTQIPETK KPAYRWLGSE SIAETGTSLF NSDEPKKRVF GTEITNLRAK  240
RNKTDCSSNG KQIGYKKHDD ANTEQESKPA ASKYVFGPSF PTGASKKNEY VRKGRLQEIE  300
SLASTYKPQY CNKGSKLNVA FLVFLAMLSA VLGGVAQESW TALFGTLYYF ISAISLVNSH  360
CLAADHSEFL NNNGENANAN AVSNPFFQFP LLPVSLPHVH SCYSCISLLL SLIL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4yo2_A	4e-16	20	200	3	228	Transcription factor E2F8
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11867638, ECO:0000269\|PubMed:15308755}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa19g003230.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010485503.1	0.0	PREDICTED: E2F transcription factor-like E2FF
Swissprot	Q8RWL0	1e-157	E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBL	R0HMF0	1e-166	R0HMF0_9BRAS; Uncharacterized protein
STRING	XP_010485503.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6003	25	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G01330.1	1e-160	DP-E2F-like protein 3

Publications ? help Back to Top
Dohmann EM, et al. The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability. Development, 2008. 135(11): p. 2013-22 [PMID:18434413]