PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa20g021460.1
Organism
Camelina sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 387aa    MW: 43531.6 Da    PI: 9.6663
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa20g021460.1genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP70.71.7e-221378171
         E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                    rkeksL+ll ++flkl+++   + + l+e+a +L    v  +rRRiYD++N+Le+++l++++ kn+++w+g
  Csa20g021460.1 13 RKEKSLGLLVSNFLKLYNRDGVDLIGLDEAAGRL---GV--ERRRIYDVVNILESIGLVARRGKNQYSWRG 78
                    79*****************999************...**..****************************98 PP
2E2F_TDP76.52.7e-24138218171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     +ke+sL++l+q+f+kl+ +s+++ +tl+ ++k+L+++      +++k+RR+YDi+NV++++nliek     ++k ++rw g
  Csa20g021460.1 138 KKERSLWQLSQSFVKLFLCSDDDLITLDGATKALLNDpqdptTMRTKVRRLYDIANVFSSMNLIEKthipeTKKAAYRWLG 218
                     699*******************************************************************999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.5E-241079IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.18E-161276IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.7E-261378IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.9E-181478IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.107.0E-20136218IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.0E-28138218IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.8E-18139218IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.35E-11141218IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 387 aa     Download sequence    Send to blast
MEALGFGHQP YSRKEKSLGL LVSNFLKLYN RDGVDLIGLD EAAGRLGVER RRIYDVVNIL  60
ESIGLVARRG KNQYSWRGFG EVPRALAELK EEGMKEKFGI VPFVTKSEMV LYEEERQESF  120
KLTPEDQDNS PLLKLDSKKE RSLWQLSQSF VKLFLCSDDD LITLDGATKA LLNDPQDPTT  180
MRTKVRRLYD IANVFSSMNL IEKTHIPETK KAAYRWLGSI DISENKSLTA SASSCDRIEP  240
KKVAYRWLGS IDISKNKLLT ASTSSCDRIE PKKRAFGTEI TNFSAKRNKA NCSKDRKHNG  300
KQNTSRAIKQ EPVDEKPDVK NFAFGSSTPA GASGMNNMGN NLRPRLGVIE ALSSMYQPQY  360
CNPAIFGLLA HYKTTFESCK EEFGRK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-3692101228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00511DAPTransfer from AT5G14960Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa20g021460.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010492317.10.0PREDICTED: E2F transcription factor-like E2FD
SwissprotQ9LFQ91e-178E2FD_ARATH; E2F transcription factor-like E2FD
TrEMBLR0GVN70.0R0GVN7_9BRAS; Uncharacterized protein
STRINGXP_010492317.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G14960.11e-175DP-E2F-like 2