PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.053540.1
Common NameCsa_3G391380, LOC101219851
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family bHLH
Protein Properties Length: 502aa    MW: 55407.4 Da    PI: 6.153
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.053540.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.78.8e-13357403455
                     HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                     +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Cucsa.053540.1 357 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAITYITDLQ 403
                     799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142156.1E-3852229IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.831353402IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474599.03E-18356416IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000836.80E-14356407No hitNo description
Gene3DG3DSA:4.10.280.106.6E-18357414IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.9E-10357403IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.2E-14359408IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS516718.535435501IPR002912ACT domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 502 aa     Download sequence    Send to blast
MGEKFWATEE KRVVVESIVG SEACEFLISL ASINILPQDS LQFSLRDSSV NQGLSQVLDG  60
SSWNYAIFWR VVTLKSGALA LIWGDGNCND SKIEIGISSV DVQGGKKEEL KTQVLQMLQS  120
SFGRSDEDGY GARRDEASDI EMLYLTSKYY KFMCDSGSSL GESYKSGKSI WASDVTSCLR  180
NYQSRGFLAK VAGLQTLVFV PVKLGVVELG STKSIPEDQG VLELVRASFG GSITAQLKAF  240
PRIFGHELSL GGTKPRSLSI NFSPKLEDDT NFSSEGYELQ GLGGNHIFGN SSNGCRGDDN  300
DAKMFPHGNQ EVVGGFNAQT RLSTMEFPRD ESSPQGDDRK PRKRGRKPAN GREEPLNHVE  360
AERQRREKLN QRFYALRAVV PNISKMDKAS LLGDAITYIT DLQMKIKVME TEKQIASGRE  420
KNTEIDFHAR EEDAVVRVSC PLDLHPVSKV IKTFREHQIE AQESNVTTST DNDKVIHSFF  480
IRTEGGAAEQ LKEKLVAALS K*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A1e-28351413264Transcription factor MYC2
5gnj_B1e-28351413264Transcription factor MYC2
5gnj_E1e-28351413264Transcription factor MYC2
5gnj_F1e-28351413264Transcription factor MYC2
5gnj_G1e-28351413264Transcription factor MYC2
5gnj_I1e-28351413264Transcription factor MYC2
5gnj_M1e-28351413264Transcription factor MYC2
5gnj_N1e-28351413264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1338346RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818350.0LN681835.1 Cucumis melo genomic scaffold, anchoredscaffold00064.
GenBankLN7132580.0LN713258.1 Cucumis melo genomic chromosome, chr_4.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011651443.10.0PREDICTED: transcription factor bHLH3
SwissprotA0A3Q7H2161e-172MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A0A0L7H20.0A0A0A0L7H2_CUCSA; Uncharacterized protein
STRINGXP_004151980.10.0(Cucumis sativus)
STRINGXP_004162392.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF82633445
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-162bHLH family protein
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  5. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  6. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]