PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.072940.1

Common Name

Csa_2G423590, LOC101212433

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 239aa MW: 26862.6 Da PI: 7.35

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.072940.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	35.8	1.4e-11	79	128	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +++ rE++RRd++N++f eL +l + + +K +K++iL A++ + +Lq Cucsa.072940.1 79 TSKACREKQRRDKLNERFLELAAVLEPG---KPPKSDKVAILSDAIRMMTDLQ 128 67889********************9...99*************99998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.97	76	127	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.8E-13	79	149	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.8E-9	79	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.14E-8	79	132	No hit	No description
SuperFamily	SSF47459	2.49E-13	81	151	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.1E-9	82	133	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 239 aa Download sequence Send to blast
MDNPPPNWNW LFDYSTVDDL AVVDPRFSPP QSISFSWSNP SINFLSKDSL EVDCSYEDLD 60 STKEVGRKRL RGETSAASTS KACREKQRRD KLNERFLELA AVLEPGKPPK SDKVAILSDA 120 IRMMTDLQCE TQKLRESKED LKAKIKELKV EKNELRDEKQ RLRAEKEKLE LQIRAVNTRA 180 ADVQHPPPTL SAAFTAQGQS AGNKLMPFIG YPGIAMWQFL PPAAVDISQD HVLRPPVA*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	65	71	GRKRLRG

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681916	1e-136	LN681916.1 Cucumis melo genomic scaffold, anchoredscaffold00037.
GenBank	LN713265	1e-136	LN713265.1 Cucumis melo genomic chromosome, chr_11.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004151873.1	1e-176	PREDICTED: transcription factor ILR3
Swissprot	Q9FH37	1e-81	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A0A0LQH8	1e-174	A0A0A0LQH8_CUCSA; Uncharacterized protein
STRING	XP_004151873.1	1e-175	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1602	34	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	5e-84	bHLH family protein

Link Out ? help Back to Top
Phytozome	Cucsa.072940.1
Entrez Gene	101212433

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]