PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.072940.2

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 188aa MW: 21156.6 Da PI: 10.3721

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.072940.2	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.4	9.2e-12	28	77	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +++ rE++RRd++N++f eL +l + + +K +K++iL A++ + +Lq Cucsa.072940.2 28 TSKACREKQRRDKLNERFLELAAVLEPG---KPPKSDKVAILSDAIRMMTDLQ 77 67889********************9...99**************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.97	25	76	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.2E-13	28	98	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.1E-9	28	77	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.75E-7	28	81	No hit	No description
SuperFamily	SSF47459	1.44E-13	30	101	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.1E-9	31	82	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 188 aa Download sequence Send to blast
MHQILYRSLI RIQIPVNRLR GETSAASTSK ACREKQRRDK LNERFLELAA VLEPGKPPKS 60 DKVAILSDAI RMMTDLQCET QKLRESKEDL KAKIKELKVE KNELRDEKQR LRAEKEKLEL 120 QIRAVNTRAA DVQHPPPTLS AAFTAQGQSA GNKLMPFIGY PGIAMWQFLP PAAVDISQDH 180 VLRPPVA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681916	1e-136	LN681916.1 Cucumis melo genomic scaffold, anchoredscaffold00037.
GenBank	LN713265	1e-136	LN713265.1 Cucumis melo genomic chromosome, chr_11.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004151873.1	1e-120	PREDICTED: transcription factor ILR3
Swissprot	Q9FH37	1e-76	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A0A0LQH8	1e-119	A0A0A0LQH8_CUCSA; Uncharacterized protein
STRING	XP_004151873.1	1e-119	(Cucumis sativus)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	5e-79	bHLH family protein

Link Out ? help Back to Top
Phytozome	Cucsa.072940.2

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]