PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.101020.1

Common Name

Csa_6G483450, LOC101222266

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 224aa MW: 24902.9 Da PI: 6.9402

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.101020.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.6	1.1e-08	123	164	8	54
HHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 8 rErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 + r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Cucsa.101020.1 123 AARLRRERISEKIRILQRLVPGG-----TKMDTASMLDEAIRYVKFL 164 6799***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.983	115	164	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	6.67E-14	120	174	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.1E-12	121	170	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.86E-11	121	169	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.2E-11	123	173	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.9E-6	123	164	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010197	Biological Process	polar nucleus fusion
GO:0005634	Cellular Component	nucleus
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 224 aa Download sequence Send to blast
MDPHHLSNPP PHLDRSAMDD HHILHHHHHV HDLDSIWPSF LPFQLSDHHD QQLPTSSTHF 60 VIGYSTPSSG TGDDEEEPEE ELGAMKEMMY KIAAMQPVDI DPSTIRKPKR RNVRISDDPQ 120 SIAARLRRER ISEKIRILQR LVPGGTKMDT ASMLDEAIRY VKFLKRQIRL LQSSQPPQQP 180 STSGGATTAG GGGGWHFPFN KANGSTSSST SMENTPAITP TGW*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	124	129	RLRRER

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription regulator required for seed dispersal. Involved in the differentiation of all three cell types required for fruit dehiscence. Acts as the key regulator in a network including SHP and ALC that controls specification of the valve margin. Works with ALC, SHP, and FUL to allow differentiation of the lignified valve layer, the spring-loaded mechanism of fruit that promotes opening. Regulates the expression of the YJ80 marker. {ECO:0000269\|PubMed:15035986}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By FUL, which restrict its expression to the margins.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681875	0.0	LN681875.1 Cucumis melo genomic scaffold, anchoredscaffold00007.
GenBank	LN713262	0.0	LN713262.1 Cucumis melo genomic chromosome, chr_8.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004148648.2	1e-165	PREDICTED: transcription factor HEC3-like
Swissprot	O81313	1e-45	IND_ARATH; Transcription factor IND
TrEMBL	A0A0A0KHS6	1e-163	A0A0A0KHS6_CUCSA; Uncharacterized protein
STRING	XP_004148648.1	1e-164	(Cucumis sativus)
STRING	XP_004169342.1	1e-164	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF651	34	141

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G00120.1	1e-46	bHLH family protein

Link Out ? help Back to Top
Phytozome	Cucsa.101020.1
Entrez Gene	101222266

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Pabón-Mora N,Wong GK,Ambrose BA Evolution of fruit development genes in flowering plants. Front Plant Sci, 2014. 5: p. 300 [PMID:25018763] Moubayidin L,Ostergaard L Dynamic control of auxin distribution imposes a bilateral-to-radial symmetry switch during gynoecium development. Curr. Biol., 2014. 24(22): p. 2743-8 [PMID:25455035] Jaradat MR,Ruegger M,Bowling A,Butler H,Cutler AJ A comprehensive transcriptome analysis of silique development and dehiscence in Arabidopsis and Brassica integrating genotypic, interspecies and developmental comparisons. GM Crops Food, 2014. 5(4): p. 302-20 [PMID:25523176] van Gelderen K,van Rongen M,Liu A,Otten A,Offringa R An INDEHISCENT-Controlled Auxin Response Specifies the Separation Layer in Early Arabidopsis Fruit. Mol Plant, 2016. 9(6): p. 857-69 [PMID:26995296] Balanzà V,Roig-Villanova I,Di Marzo M,Masiero S,Colombo L Seed abscission and fruit dehiscence required for seed dispersal rely on similar genetic networks. Development, 2016. 143(18): p. 3372-81 [PMID:27510967] Pfannebecker KC,Lange M,Rupp O,Becker A Seed Plant-Specific Gene Lineages Involved in Carpel Development. Mol. Biol. Evol., 2017. 34(4): p. 925-942 [PMID:28087776] He H, et al. CELLULASE6 and MANNANASE7 Affect Cell Differentiation and Silique Dehiscence. Plant Physiol., 2018. 176(3): p. 2186-2201 [PMID:29348141] Simonini S,Stephenson P,Østergaard L A molecular framework controlling style morphology in Brassicaceae. Development, 2018. [PMID:29440299] Li XR,Deb J,Kumar SV,Østergaard L Temperature Modulates Tissue-Specification Program to Control Fruit Dehiscence in Brassicaceae. Mol Plant, 2018. 11(4): p. 598-606 [PMID:29449088]