PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.104330.1
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family C2H2
Protein Properties Length: 237aa    MW: 26540.4 Da    PI: 8.0408
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.104330.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H223.61.3e-074364223
                    EETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  2 kCpdCgksFsrksnLkrHirtH 23
                     C++Cgk F+r  nL+ H+r H
  Cucsa.104330.1 43 FCEICGKGFKRDANLRMHMRAH 64
                    6*******************99 PP
2zf-C2H212.10.0006163178621
                     TTEEESSHHHHHHHHH CS
         zf-C2H2   6 CgksFsrksnLkrHir 21 
                     Cg++Fsrk+ L  H+ 
  Cucsa.104330.1 163 CGTTFSRKDKLFGHMA 178
                     **************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.36E-63965No hitNo description
PROSITE profilePS5015711.9674269IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.1E-64264IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.00154264IPR015880Zinc finger, C2H2-like
PfamPF128740.00114362No hitNo description
PROSITE patternPS0002804464IPR007087Zinc finger, C2H2
SMARTSM0035510093126IPR015880Zinc finger, C2H2-like
SMARTSM0035518131153IPR015880Zinc finger, C2H2-like
SMARTSM00355210159183IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 237 aa     Download sequence    Send to blast
KSMAELKVEG ADEIAITESE EFDPDWEIVE LDAMELLAEH IHFCEICGKG FKRDANLRMH  60
MRAHGNQFKT PEALAKPLDV VVGADHRAKR TRFSCPYDGC VRNKMHKKFR ALKSLICVKN  120
HFKRSHCPKM FSCNRCNKKS FSVMADLKSH LKHCGESKWR CSCGTTFSRK DKLFGHMALF  180
EGHMPAVPDD ACPTTATTSG MDEDGESNQI SKDGNLQNGS IYLEAMRSSS HGVVQL*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818750.0LN681875.1 Cucumis melo genomic scaffold, anchoredscaffold00007.
GenBankLN7132620.0LN713262.1 Cucumis melo genomic chromosome, chr_8.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004143557.11e-165PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
SwissprotQ9C8N57e-80STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA0A0A0KGR61e-163A0A0A0KGR6_CUCSA; Uncharacterized protein
STRINGXP_004143557.11e-164(Cucumis sativus)
STRINGXP_004168999.11e-164(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF68553150
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.31e-83C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]