PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.122930.1
Common NameCsa_4G630010, LOC101213540
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family ERF
Protein Properties Length: 194aa    MW: 21043.2 Da    PI: 8.4728
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.122930.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP263.25.6e-201969256
             AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56
                    +y+GVr ++ +gr++AeIrdp++   ++r++lg+f taeeAa+a++aa+++++g+
  Cucsa.122930.1 19 RYRGVRKRP-WGRYAAEIRDPRK---KTRVWLGTFNTAEEAARAYDAAAREFRGA 69
                    59*******.**********843...6*************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541714.71E-231977IPR016177DNA-binding domain
PROSITE profilePS5103224.5791976IPR001471AP2/ERF domain
CDDcd000181.02E-181976No hitNo description
Gene3DG3DSA:3.30.730.101.4E-321977IPR001471AP2/ERF domain
SMARTSM003801.4E-361982IPR001471AP2/ERF domain
PfamPF008474.3E-141968IPR001471AP2/ERF domain
PRINTSPR003671.7E-112031IPR001471AP2/ERF domain
PRINTSPR003671.7E-114258IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 194 aa     Download sequence    Send to blast
MAAGDRSTST TPPTSKEIRY RGVRKRPWGR YAAEIRDPRK KTRVWLGTFN TAEEAARAYD  60
AAAREFRGAN AKTNFPLQTD FLIVDNNNHS NFHKSACSTS PSHSSTVESS SPSPTPSDPY  120
LDGGIHPPGI SPPIFFFDAF AQAEKNISDF RRTVTAAVAG ASDSDSSSVG DFDTTRKSRP  180
LDFDLNLPAV EVV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A9e-2219811477Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways, and could also regulate other AtERFs. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11487705, ECO:0000269|PubMed:9756931}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by jasmonate (JA) and by Alternaria brassicicola (locally and systemically), but only slightly by ethylene. Strong induction by wounding, cold or drought stress does not require EIN2, whereas induction by NaCl does. Transcripts accumulate in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), and heat stress. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:12805630}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818620.0LN681862.1 Cucumis melo genomic scaffold, anchoredscaffold00081.
GenBankLN7132610.0LN713261.1 Cucumis melo genomic chromosome, chr_7.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004146050.11e-139PREDICTED: ethylene-responsive transcription factor 4
SwissprotO803405e-38ERF78_ARATH; Ethylene-responsive transcription factor 4
TrEMBLA0A0A0L4P11e-138A0A0A0L4P1_CUCSA; Ethylene response factor 2
STRINGXP_004146050.11e-139(Cucumis sativus)
STRINGXP_004162927.11e-139(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33034189
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G15210.19e-23ethylene responsive element binding factor 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Cao WH, et al.
    Modulation of ethylene responses affects plant salt-stress responses.
    Plant Physiol., 2007. 143(2): p. 707-19
    [PMID:17189334]
  3. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  4. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  5. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  6. Lyons R, et al.
    The RNA-binding protein FPA regulates flg22-triggered defense responses and transcription factor activity by alternative polyadenylation.
    Sci Rep, 2013. 3: p. 2866
    [PMID:24104185]
  7. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  8. Gao S, et al.
    A cotton miRNA is involved in regulation of plant response to salt stress.
    Sci Rep, 2016. 6: p. 19736
    [PMID:26813144]
  9. Zhou X, et al.
    The ERF11 Transcription Factor Promotes Internode Elongation by Activating Gibberellin Biosynthesis and Signaling.
    Plant Physiol., 2016. 171(4): p. 2760-70
    [PMID:27255484]
  10. Liu W, et al.
    The ethylene response factor AtERF4 negatively regulates the iron deficiency response in Arabidopsis thaliana.
    PLoS ONE, 2017. 12(10): p. e0186580
    [PMID:29045490]