PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.198520.1

Common Name

Csa_1G015080, LOC101211973

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 560aa MW: 61190 Da PI: 8.8034

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.198520.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	53.6	4e-17	259	308	2	55
HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r +h++ E+rRR++iN++f+ Lr l+P++ ++K +Ka+ L ++veYI+ Lq Cucsa.198520.1 259 RSKHSATEQRRRSKINDRFQMLRGLIPHS----DQKRDKASFLLEVVEYIQFLQ 308 889***********************9....9*****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	3.2E-25	254	329	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	5.89E-19	256	327	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	16.437	257	307	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	8.06E-15	259	312	No hit	No description
Pfam	PF00010	1.3E-14	259	308	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.2E-13	263	313	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006351	Biological Process	transcription, DNA-templated
GO:0009742	Biological Process	brassinosteroid mediated signaling pathway
GO:1902448	Biological Process	positive regulation of shade avoidance
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 560 aa Download sequence Send to blast
MELPQPRPFG AEGSKSTHDF LSLYTHSSPQ LDPRSTPQGS YLKTHDFLQP QERIRKASTK 60 EETDVERPPP PAPPPSVEHI LPGGIGTYSI SHVSYFDQRV VLPKPEGSVF TGVRSSSSAE 120 RNDENSNCSS FAAAGSGFTL WEESSVKKGK TGKENNVGDR PHEPRASTSQ WTASMERPSQ 180 SSSNNHHNTF SCLSSSQPTG TKNPTFMEML KSAKSTSQDE ELDDDGDFVI KKETSTANKG 240 GLRIKVDGNS SDQKANTPRS KHSATEQRRR SKINDRFQML RGLIPHSDQK RDKASFLLEV 300 VEYIQFLQEK VQKYEGSYQE WNHEMAKLVP LRNNQRSADV YNDQSRGINS GSVPALVLAA 360 KFIEKNSPLS PIVPGSAHNA VDSDTSSAST LKAVDHHSGR TSNAVQFPMS IPPKLSASTR 420 DGNVVPQPPK PLSSGMDHSS LRPEIRSCEA RCFNSDVAVA SEMQKEQDLT IEGGTINISS 480 VYSQGLLNTL THALQSSGVD LSQARISVQI ELGKRASRRA ISPASIVKDA NDMGMMHARV 540 SGTEDSERAT KKLKTTMKN*

Sequence ? help Back to Top

Protein Sequence Length: 560 aa Download sequence Send to blast

MELPQPRPFG AEGSKSTHDF LSLYTHSSPQ LDPRSTPQGS YLKTHDFLQP QERIRKASTK  60
EETDVERPPP PAPPPSVEHI LPGGIGTYSI SHVSYFDQRV VLPKPEGSVF TGVRSSSSAE  120
RNDENSNCSS FAAAGSGFTL WEESSVKKGK TGKENNVGDR PHEPRASTSQ WTASMERPSQ  180
SSSNNHHNTF SCLSSSQPTG TKNPTFMEML KSAKSTSQDE ELDDDGDFVI KKETSTANKG  240
GLRIKVDGNS SDQKANTPRS KHSATEQRRR SKINDRFQML RGLIPHSDQK RDKASFLLEV  300
VEYIQFLQEK VQKYEGSYQE WNHEMAKLVP LRNNQRSADV YNDQSRGINS GSVPALVLAA  360
KFIEKNSPLS PIVPGSAHNA VDSDTSSAST LKAVDHHSGR TSNAVQFPMS IPPKLSASTR  420
DGNVVPQPPK PLSSGMDHSS LRPEIRSCEA RCFNSDVAVA SEMQKEQDLT IEGGTINISS  480
VYSQGLLNTL THALQSSGVD LSQARISVQI ELGKRASRRA ISPASIVKDA NDMGMMHARV  540
SGTEDSERAT KKLKTTMKN*

Functional Description ? help Back to Top
Source	Description
UniProt	Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. {ECO:0000269\|PubMed:15680330}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00498	DAP	Transfer from AT5G08130	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by cold treatment. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681813	0.0	LN681813.1 Cucumis melo genomic scaffold, anchoredscaffold00030.
GenBank	LN713256	0.0	LN713256.1 Cucumis melo genomic chromosome, chr_2.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011648566.1	0.0	PREDICTED: transcription factor BIM1
Swissprot	Q9LEZ3	1e-113	BIM1_ARATH; Transcription factor BIM1
TrEMBL	A0A0A0LSI8	0.0	A0A0A0LSI8_CUCSA; Uncharacterized protein
STRING	XP_004138212.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7252	31	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G08130.4	1e-117	bHLH family protein

Link Out ? help Back to Top
Phytozome	Cucsa.198520.1
Entrez Gene	101211973

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]