PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.255290.1

Common Name

Csa_3G135660, LOC101210812

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 227aa MW: 25536.8 Da PI: 5.9224

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.255290.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	33	1.1e-10	75	122	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rEr RR+++N++f L l ++ +++K +K +iL A++ +++L Cucsa.255290.1 75 SKACRERLRREKLNDRFLDLSIALEPS---RHTKTNKPAILDDAIRVLNQL 122 5678*********************...****************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	11.839	71	122	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.22E-7	74	127	No hit	No description
SuperFamily	SSF47459	1.7E-12	74	142	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.0E-11	75	144	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	7.6E-8	75	122	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.0E-8	77	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 227 aa Download sequence Send to blast
MDPLEDSSCW DFLDCSFFPD ADNLINPSLH PFWPPNHSRR DSLADTDVSA GHLESEENDC 60 SRKRARDGSC AGASSKACRE RLRREKLNDR FLDLSIALEP SRHTKTNKPA ILDDAIRVLN 120 QLKNEAEELK QTNEKLREEV ESLKAEKNDL RKEKIILKED KEKMEQQLKS IAIPSPGLIP 180 GHPAAYHAAS GKMAVFPGYG LIPMWQYLPP SIRDTSQDHE LRPPAA*

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00102	PBM	Transfer from AT4G14410	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681848	1e-123	LN681848.1 Cucumis melo genomic scaffold, anchoredscaffold00006.
GenBank	LN713260	1e-123	LN713260.1 Cucumis melo genomic chromosome, chr_6.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004134070.1	1e-166	PREDICTED: transcription factor bHLH104-like
Swissprot	Q8L467	2e-77	BH104_ARATH; Transcription factor bHLH104
TrEMBL	A0A0A0L755	1e-165	A0A0A0L755_CUCSA; Uncharacterized protein
STRING	XP_004134070.1	1e-166	(Cucumis sativus)
STRING	XP_004169970.1	1e-166	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8179	25	37

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.2	3e-71	bHLH family protein

Link Out ? help Back to Top
Phytozome	Cucsa.255290.1
Entrez Gene	101210812

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]