PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.337510.1

Common Name

Csa_3G817710, LOC101215342

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bZIP

Protein Properties

Length: 722aa MW: 78470.3 Da PI: 6.8535

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.337510.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	41.1	4e-13	221	282	2	63
XXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 2 kelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 + kr r+++NRe+A+ sRqRKk ++eeLe+kv ++ + +L ++++ + e a l++++ Cucsa.337510.1 221 DDEKRKARLMRNRESAQLSRQRKKHYVEELEDKVRNMHSTIAELNSKISYIMAENAGLRQQL 282 5679**********************************************999999998875 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	2.8E-17	220	284	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.622	222	282	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	2.9E-11	223	282	IPR004827	Basic-leucine zipper domain
Gene3D	G3DSA:1.20.5.170	1.8E-17	224	283	No hit	No description
SuperFamily	SSF57959	4.88E-12	224	282	No hit	No description
CDD	cd14704	3.44E-22	225	276	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0042538	Biological Process	hyperosmotic salinity response
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005783	Cellular Component	endoplasmic reticulum
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 722 aa Download sequence Send to blast
MPDPFHPVSP SDQNPNSTSY ASEFDSLPIP PLDSLFFSDP NHDGPGDPFL YSTALDLGFD 60 DNDDFELTFD DLDDLCLPSE ADDFLISDNL DHPTNSPHLP PDVPLEDDSS VPVCSPAGSP 120 GSGSSAVSCH PSPHDCGPAS SQGSGSGVSE GMNCPSSNAE CYDVIVDQKV KSEEMGKNCM 180 TKRKKEQDEG NADFRSAKYQ RSSVSTEATN PQLDPCSINE DDEKRKARLM RNRESAQLSR 240 QRKKHYVEEL EDKVRNMHST IAELNSKISY IMAENAGLRQ QLSGSGMCQP PPPGMFPHPS 300 MPPMPPMPYS WMPCAPYVVK PQGSQVPLVP IPRLKPQQPI PVARGKKTES KKTEGRTKKA 360 ASVSFLGLLF FIMVFGGLVP LANDRFGNVG VVPGKLSFVG DNRLYNQNQG RVLRVDEHSN 420 LSDGVNVGTH CGKSGTLNRL QCERIYRKGR DLNFDQRGKE SQRLNDSDES VKLRNAREPL 480 VASLYVPRND KLVKIDGNLI IHSFLASEKA MASGKASDTD KARETGLAIP RDLSPALTIP 540 NIRALPSGPA NRDHKKATAV DGKLQQWFRE GLAGPMLSSG LCTEVFQFDV SSTAPGAIVP 600 ASSLVNTSKT HRKNGTHLNK GKNRRILGGL PVPLSRSNFN ITEEPVRNPH KDNFPGNNNK 660 TASSVVVSVL IDPREAGDSE VDGVITPKSL SRIFVVVLLD SVKYVTYSCV LPRSGPHLVS 720 T*

Sequence ? help Back to Top

Protein Sequence Length: 722 aa Download sequence Send to blast

MPDPFHPVSP SDQNPNSTSY ASEFDSLPIP PLDSLFFSDP NHDGPGDPFL YSTALDLGFD  60
DNDDFELTFD DLDDLCLPSE ADDFLISDNL DHPTNSPHLP PDVPLEDDSS VPVCSPAGSP  120
GSGSSAVSCH PSPHDCGPAS SQGSGSGVSE GMNCPSSNAE CYDVIVDQKV KSEEMGKNCM  180
TKRKKEQDEG NADFRSAKYQ RSSVSTEATN PQLDPCSINE DDEKRKARLM RNRESAQLSR  240
QRKKHYVEEL EDKVRNMHST IAELNSKISY IMAENAGLRQ QLSGSGMCQP PPPGMFPHPS  300
MPPMPPMPYS WMPCAPYVVK PQGSQVPLVP IPRLKPQQPI PVARGKKTES KKTEGRTKKA  360
ASVSFLGLLF FIMVFGGLVP LANDRFGNVG VVPGKLSFVG DNRLYNQNQG RVLRVDEHSN  420
LSDGVNVGTH CGKSGTLNRL QCERIYRKGR DLNFDQRGKE SQRLNDSDES VKLRNAREPL  480
VASLYVPRND KLVKIDGNLI IHSFLASEKA MASGKASDTD KARETGLAIP RDLSPALTIP  540
NIRALPSGPA NRDHKKATAV DGKLQQWFRE GLAGPMLSSG LCTEVFQFDV SSTAPGAIVP  600
ASSLVNTSKT HRKNGTHLNK GKNRRILGGL PVPLSRSNFN ITEEPVRNPH KDNFPGNNNK  660
TASSVVVSVL IDPREAGDSE VDGVITPKSL SRIFVVVLLD SVKYVTYSCV LPRSGPHLVS  720
T*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in salt and osmotic stress responses. Functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes (PubMed:17662035). Functions as a stress sensor and transducer in ER stress signaling pathway. ER stress induces proteolysis of BZIP17 by SBT6.1 (S1P) and S2P, and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones, as well as protein involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269\|PubMed:17662035, ECO:0000269\|PubMed:20876872}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681841	0.0	LN681841.1 Cucumis melo genomic scaffold, anchoredscaffold00011.
GenBank	LN713258	0.0	LN713258.1 Cucumis melo genomic chromosome, chr_4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004136623.1	0.0	PREDICTED: bZIP transcription factor 17-like
Swissprot	O22208	1e-173	BZP17_ARATH; bZIP transcription factor 17
TrEMBL	A0A0A0LHA7	0.0	A0A0A0LHA7_CUCSA; Uncharacterized protein
STRING	XP_004136623.1	0.0	(Cucumis sativus)
STRING	XP_004167786.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7487	34	48

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G40950.1	1e-157	bZIP family protein

Link Out ? help Back to Top
Phytozome	Cucsa.337510.1
Entrez Gene	101215342

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Zhou SF, et al. Membrane-associated transcription factor peptidase, site-2 protease, antagonizes ABA signaling in Arabidopsis. New Phytol., 2015. 208(1): p. 188-97 [PMID:25919792] Sagor GH, et al. The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis. Front Plant Sci, 2015. 6: p. 687 [PMID:26442007] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kim JS,Yamaguchi-Shinozaki K,Shinozaki K ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation. Plant Physiol., 2018. 176(3): p. 2221-2230 [PMID:29367234] Cifuentes-Esquivel N, et al. bZIP17 regulates the expression of genes related to seed storage and germination, reducing seed susceptibility to osmotic stress. J. Cell. Biochem., 2018. 119(8): p. 6857-6868 [PMID:29693271] Guan P, et al. SENSITIVE TO SALT1, An Endoplasmic Reticulum-Localized Chaperone, Positively Regulates Salt Resistance. Plant Physiol., 2018. 178(3): p. 1390-1405 [PMID:30287478]