PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_010210
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family HD-ZIP
Protein Properties Length: 719aa    MW: 79960.7 Da    PI: 6.622
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_010210genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.26.8e-192681156
                 TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
     Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                 +++ +++t++q++ Le  F++ ++p++++r +L+++lgL+ rq+k+WFqNrR+++k
  DCAR_010210 26 KKRYHRHTADQIQKLEGIFKEFPHPDEKMRLQLSRELGLSPRQIKFWFQNRRTQMK 81
                 688999***********************************************998 PP
2START171.84.5e-542254483206
                  HHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEEC CS
        START   3 aeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetlevis 86 
                  a   + el+++ +++ep+W+ks     e +n + + ++f++ ++       ++ea+r+sgvv+m+   lv+ ++d++ +W e ++    +a+t+evis
  DCAR_010210 225 AGNSMGELIRLLQSNEPFWMKSIadgkEVLNLESYERIFPRINShlknpnVHIEASRDSGVVIMNGLALVNMFMDSN-KWVELFPtivsRAATIEVIS 321
                  667889*****************99887888888888887766699*******************************.******99999********* PP

                  TT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX CS
        START  87 sg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlp 177
                  s       g lqlm++elq+lsplvp R f f+R+++q ++g+w++vdvS d +q+++   s   +++lpSg+li++++ng+skv w+eh+++++++p
  DCAR_010210 322 SErmgsqsGSLQLMYQELQVLSPLVPtRQFCFLRFCQQIEQGSWALVDVSYDLPQNNT-FTSQCQVQRLPSGCLIQDMPNGYSKVSWMEHMEVEDKVP 418
                  **********************************************************.799999********************************* PP

                  .HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
        START 178 .hwllrslvksglaegaktwvatlqrqcek 206
                   h l+r  + sg a+ga +w +tlqr+ce+
  DCAR_010210 419 iHRLYRDHIYSGFAFGAERWISTLQRSCER 448
                  ****************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.605.5E-20785IPR009057Homeodomain-like
SuperFamilySSF466893.76E-191283IPR009057Homeodomain-like
PROSITE profilePS5007117.3462383IPR001356Homeobox domain
SMARTSM003896.3E-192487IPR001356Homeobox domain
CDDcd000862.93E-182584No hitNo description
PfamPF000462.4E-162681IPR001356Homeobox domain
PROSITE patternPS0002705881IPR017970Homeobox, conserved site
SuperFamilySSF559617.97E-33214449No hitNo description
PROSITE profilePS5084847.636214451IPR002913START domain
CDDcd088752.10E-110218447No hitNo description
SMARTSM002342.7E-45223448IPR002913START domain
PfamPF018521.7E-46225448IPR002913START domain
Gene3DG3DSA:3.30.530.202.3E-4293418IPR023393START-like domain
SuperFamilySSF559612.47E-19469680No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 719 aa     Download sequence    Send to blast
MEFGSAGAGG GSGDDHYDAF DPYRRKKRYH RHTADQIQKL EGIFKEFPHP DEKMRLQLSR  60
ELGLSPRQIK FWFQNRRTQM KAQHERADNC ALRSENDKIR CENIAIREAL RNVICPSCGG  120
LPGGEDPYFD EQKLRIQNSQ LKEELDRISN MAGRYIGRPI SQLPPIQPFH ISSLDLSMGS  180
FGFQGMPGPS FDLDLLPGSS SNVPNIPYQR VSLTDMDKSL MADIAGNSMG ELIRLLQSNE  240
PFWMKSIADG KEVLNLESYE RIFPRINSHL KNPNVHIEAS RDSGVVIMNG LALVNMFMDS  300
NKWVELFPTI VSRAATIEVI SSERMGSQSG SLQLMYQELQ VLSPLVPTRQ FCFLRFCQQI  360
EQGSWALVDV SYDLPQNNTF TSQCQVQRLP SGCLIQDMPN GYSKVSWMEH MEVEDKVPIH  420
RLYRDHIYSG FAFGAERWIS TLQRSCERIA CSLVIGPSIH DIGGGITSPD GKRSMMKLSQ  480
RMVNNFCSII NLPNSQQWTA LFGTDELEVR ASIHKFTNPG QSHGMVLSAA TTIWLPVPSQ  540
IVFNFFKDER TRAQWDVLSD QNPVHEVAHI ANGSHPGNCI SVLRAFNTSQ SNMLVLQESC  600
IDSSGSLVVY SPVDLHSINI AMSGEDPSFI PLLPSGFTIS PDGKTDISQH SKSHDQGASS  660
SSATTTSGSL LTIVIQIMVS HNMASSGPKM SQESVNTVNN LMGNTVQQIK VALNCSSC*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017240757.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A166ALN60.0A0A166ALN6_DAUCS; Uncharacterized protein
STRINGXP_010099679.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]