PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

DCAR_015480

Organism

Daucus carota

Taxonomic ID

4039

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus

Family

C2H2

Protein Properties

Length: 357aa MW: 39015.4 Da PI: 4.4926

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
DCAR_015480	genome	ARS-USDA	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14	0.00015	331	353	2	23
EETTTTEEESSHHHHHHHHHH.T CS zf-C2H2 2 kCpdCgksFsrksnLkrHirt.H 23 +C+ C+k+F++ L++H + H DCAR_015480 331 TCKSCSKTFNSEKGLESHSKAkH 353 7*****************88777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50157	10.97	330	356	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	332	353	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 357 aa Download sequence Send to blast
MEFWGVEVKA GEPLHVAPED GELIHISQVA LGEVKNVKSA NYVPVRLQVD DKKYVIGTLS 60 AEKAPQIMFD LVLEKDFTLS HDWKDGSLYF CGYTAAAEGE YPFLCDIFLP IYWVYIRVLS 120 FLKLMPSISK LCPGNVFFSQ VTDVSFLLLY NVSLTFVIFS TDDDGQFGEA RPDLKFSDFS 180 DEDESEDEEI IEKGKPVADV QAAVPAKSKA AAAKEGTSAK PKVTLVDPKK EDSDDSEDSD 240 EDSDDESEDD LDDDDSDDGM SEDEETPKKV ESSKKRPSGS EIKTPASIKK SKTETPQKTD 300 GKKGAHTATP HPAKKSDKKA AETPKSSGQV TCKSCSKTFN SEKGLESHSK AKHGGK*

Sequence ? help Back to Top

Protein Sequence Length: 357 aa Download sequence Send to blast

MEFWGVEVKA GEPLHVAPED GELIHISQVA LGEVKNVKSA NYVPVRLQVD DKKYVIGTLS  60
AEKAPQIMFD LVLEKDFTLS HDWKDGSLYF CGYTAAAEGE YPFLCDIFLP IYWVYIRVLS  120
FLKLMPSISK LCPGNVFFSQ VTDVSFLLLY NVSLTFVIFS TDDDGQFGEA RPDLKFSDFS  180
DEDESEDEEI IEKGKPVADV QAAVPAKSKA AAAKEGTSAK PKVTLVDPKK EDSDDSEDSD  240
EDSDDESEDD LDDDDSDDGM SEDEETPKKV ESSKKRPSGS EIKTPASIKK SKTETPQKTD  300
GKKGAHTATP HPAKKSDKKA AETPKSSGQV TCKSCSKTFN SEKGLESHSK AKHGGK*

Functional Description ? help Back to Top
Source	Description
UniProt	Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Required for histone H3 'Lys-9' deacetylation. Involved in rRNA gene silencing in nucleolar dominance. Seems to be implicated in the regulation of genes involved in seeds development. {ECO:0000269\|PubMed:10792817, ECO:0000269\|PubMed:12694598, ECO:0000269\|PubMed:14992728, ECO:0000269\|PubMed:15144374}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017244259.1	4e-68	PREDICTED: histone deacetylase HDT1-like isoform X1
Swissprot	Q9FVE6	1e-30	HDT1_ARATH; Histone deacetylase HDT1
TrEMBL	A0A165A9Q3	0.0	A0A165A9Q3_DAUCS; Uncharacterized protein

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA11138	2	2

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G44750.2	4e-32	histone deacetylase 3

Link Out ? help Back to Top
Phytozome	DCAR_015480

Publications ? help Back to Top
Song Y,Wu K,Dhaubhadel S,An L,Tian L Arabidopsis DNA methyltransferase AtDNMT2 associates with histone deacetylase AtHD2s activity. Biochem. Biophys. Res. Commun., 2010. 396(2): p. 187-92 [PMID:20331964] Lee K,Park OS,Jung SJ,Seo PJ Histone deacetylation-mediated cellular dedifferentiation in Arabidopsis. J. Plant Physiol., 2016. 191: p. 95-100 [PMID:26724747] Han Z, et al. AtHD2D Gene Plays a Role in Plant Growth, Development, and Response to Abiotic Stresses in Arabidopsis thaliana. Front Plant Sci, 2016. 7: p. 310 [PMID:27066015] Li H, et al. Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-OXIDASE2 Expression to Control Arabidopsis Root Meristem Cell Number. Plant Cell, 2017. 29(9): p. 2183-2196 [PMID:28855334]