PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Dca26940.1
Organism
Dianthus caryophyllus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Caryophyllaceae; Caryophylleae; Dianthus
Family E2F/DP
Protein Properties Length: 341aa    MW: 38340.8 Da    PI: 9.9327
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Dca26940.1genomeDCAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP68.11.1e-211075171
     E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                rk+ksL+ll+++fl+l+++   + ++l+++a +L    v  +rRRiYDi+NVLe +++++kk+kn+++ kg
  Dca26940.1 10 RKQKSLGLLCSNFLRLYNRDGVDLICLDDAALKL---GV--ERRRIYDIVNVLENVGMVTKKAKNQYTMKG 75
                79*****************999************...**..**************************9987 PP
2E2F_TDP71.97.2e-23128207171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek....kekneirwkg 71 
                 rkeksL+lltq+f+kl+ +s+ ++++l+e+ak L+ +      +++k RR+YDi+NVL++++liek    ++k++ rw g
  Dca26940.1 128 RKEKSLGLLTQNFVKLFLCSNFKQISLDEAAKFLLGDglnagVMRTKIRRLYDIANVLSSVQLIEKtqtdSRKPAWRWLG 207
                 79***************************************9999*********************99999999999987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.7E-22775IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467859.14E-14971IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.8E-231075IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.4E-181173IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.2E-21126208IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.3E-26128207IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.2E-18129207IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467857.26E-13130208IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 341 aa     Download sequence    Send to blast
MASSEDGYNR KQKSLGLLCS NFLRLYNRDG VDLICLDDAA LKLGVERRRI YDIVNVLENV  60
GMVTKKAKNQ YTMKGYAGIP HALALLKDEG LKENFVSSAG RRRIQIIDLE DDANADFGPN  120
GASKLENRKE KSLGLLTQNF VKLFLCSNFK QISLDEAAKF LLGDGLNAGV MRTKIRRLYD  180
IANVLSSVQL IEKTQTDSRK PAWRWLGMGE RTGFTVSAFP VSTETKKRSF GTDISNVSFK  240
RPNVEREAAK QAKSECADKK LLTAYLEQDP KSRSQSCRYG PFAPVIVSKK TKHNRDLEAL  300
AASHRPQYHN EAVKDLFEHY VEAWRSWYSE LAGKTSVSLV S
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A4e-3892013232Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010678680.11e-146PREDICTED: E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ41e-104E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A0K9R2D51e-134A0A0K9R2D5_SPIOL; Uncharacterized protein
STRINGXP_010678681.11e-143(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-106DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]